| Cat. No. |
Product Name |
Information |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-26995 |
SIPI11594
MPC inhibitor
|
SIPI11594 is a small molecule mitochondrial pyruvate carrier (MPC) inhibitor, shows cellular lactate production-enhancing activity, significantly accelerates hair regrowth and anagen entry. |
| PC-26982 |
Zearalenone
Endocrine disruptor
|
Zearalenone (Mycotoxin F2, Toxin F2) is a potent endocrine disruptor that poses serious health risks through reproductive toxicity. |
| PC-26955 |
UCM-1336
ICMT inhibitor
|
UCM-1336 is a potent, selective isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor with IC50 of 2 uM. |
| PC-26951 |
AGPS-IN-1
AGPS inhibitor
|
AGPS-IN-1 (AGPS inhibitor 2i) is a small molecule inhibitor of alkylglyceronephosphate synthase (AGPS), decreases ether lipids, cell migration and survival, specifically impairs EMT through E-cadherine, Snail, Mmp2 modulation. |
| PC-26941 |
NCGC00138783 TFA
CD47/SIRPα inhibitor
|
NCGC00138783 TFA is a selective inhibitor targeting CD47/SIRPα axis with IC50 of 50 µM, directly blocks the interaction between CD47 and SIRPα. |
| PC-26940 |
NCGC00138783
CD47/SIRPα inhibitor
|
NCGC00138783 is a selective inhibitor targeting CD47/SIRPα axis with IC50 of 50 µM, directly blocks the interaction between CD47 and SIRPα. |
| PC-26939 |
NCGC00092410
GCase inhibitor
|
NCGC00092410 is a potent, selective and nonsugar glucocerebrosidase (GC, GCase) inhibitor with IC50 of 31 nM. |
| PC-26936 |
NCGC00685960
NNMT inhibitor
|
NCGC00685960 is a highly potent, specific Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50 of <10 nM, increases H3K27 trimethylation levels in ovarian cancer cells and inhibits α-SMA expression in NNMT-expressing ovarian fibroblasts, has potent antitumor activity. |
| PC-26933 |
β-actin inhibitor C25
β-actin inhibitor
|
β-actin inhibitor C25 is potent, selective and covalent inhibitor of beta-actin (β-actin), does not target α- or γ-actin, inhibits β-Actin polymerization to disrupt the actin cytoskeleton and lead to cell death in143B cells (IC50=15 nM), selectively and covalently binds to Cys272 in β-actin. |
