| Cat. No. |
Product Name |
Information |
| PC-25362 |
Dracorhodin perchlorate
CD147 inhibitor
|
Dracorhodin perchlorate is a potent CD147 inhibitor that induces autophagy-dependent degradation, triggers PUFA/MUFA balance-mediated ferroptosis. |
| PC-25339 |
CQ3196
RIOK2 inhibitor
|
CQ3196 is a potent and orally bioavailable RIO kinase 2 (RIOK2) inhibitor with binding Kd of 14 nM, suppresses RIOK2 ATPase activity in vitro with IC50 of 72 nM in an ADP-Glo kinase assays. |
| PC-25307 |
SyntOFF
Syntenin inhibitor
|
SyntOFF is a specific small molecule inhibitor of syntenin with IC50 of 37 uM in HTRF assays, targets the PDZ2 domain of syntenin. |
| PC-25281 |
KI-DX-014
DDX21 inhibitor
|
KI-DX-014 is a specific small-molecule compound capable of inhibiting the interaction of DDX21 with RNA with IC50 of 3.31 uM, directly binds to DDX21-C-terminal domain (HC+CTD) with Kd of 15.9 uM, allosterically attenuates DDX21 ATPase activity. |
| PC-25222 |
ASS1 inhibitor C-01
ASS1 inhibitor
|
ASS1 inhibitor C-01 is a small molecule inhibitor of argininosuccinate synthetase 1 (ASS1), binds to ASS1 directly with SPR Kd of 18.8 nM. |
| PC-25184 |
JX-078
LAT1 inhibitor
|
JX-078 is a potent, selective inhibitor of L-type amino acid transporters LAT1 (SLC7A5), inhibits [3H]-L-leucine uptake into HT-29 cells with IC50 of 121 nM, >10-fold selective over in LAT2. |
| PC-25146 |
BI033
BACH1 inhibitor
|
BI033 is a selective small-molecule BTB and CNC homology 1 (BACH1) inhibitor, specifically binds to BACH1 WT with Kd of 9.0 uM, significantly upregulates HO-1 mRNA and protein expression. |
| PC-25105 |
DEL-S1
SLIT2/ROBO1 inhibitor
|
DEL-S1 is a first-in-class small molecule that binds to SLIT2 and disrupts its interaction with ROBO1 with IC50 of 68.8 uM in TR-FRET assays. |
| PC-25013 |
TREM2 agonist C1
TREM2 agonist
|
TREM2 agonist C1 is a structural analog of VG-3927 and small molecule agonist of triggering receptor expressed on myeloid cells 2 (TREM2) with KD of 71.36 uM in MST assays. |
| PC-24950 |
Eloralintide sodium
Amylin receptor agonist
|
Eloralintide sodium (LY3841136) is a selective amylin mimetic and long acting amylin receptor (AMYR) agonist, binds to amylin receptors with high selectivity from calcitonin receptors. |
| PC-24949 |
Eloralintide
Amylin receptor agonist
|
Eloralintide (LY3841136) is a selective amylin mimetic and long acting amylin receptor (AMYR) agonist, binds to amylin receptors with high selectivity from calcitonin receptors. |
| PC-24839 |
NGI-186
Oligosaccharyltransferase inhibitor
|
NGI-186 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.06 uM. |
