| Cat. No. |
Product Name |
Information |
| PC-45088 |
SP-420
Iron chelating agent
|
Petadeferitrin (SP-420) is a desferrithiocin analogue and iron chelating agent that has iron-clearing efficiency with ICE value of 26.7, SP-420 is more potent than desferrithiocin. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-26639 |
Auxinole
Auxin antagonist
|
Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and inhibits auxin-responsive gene expression. |
| PC-26624 |
S720-2261
FIBCD1 inhibitor
|
S720-2261 is a small molecule inhibitor of FIBCD1 (Fibrinogen C domain-containing protein 1) with SPR KD of 585 uM. |
| PC-26623 |
CTI-2
PNC inhibitor
|
CTI-2 is a small molecule inhibitor of perinucleolar compartment (PNC), shows potential anti-AML activity against FLT3-ITD mutant AML. |
| PC-26621 |
BCAT2 inhibitor C11
BACT2 inhibitor
|
BCAT2 inhibitor C11 is a potent, selective branched-chain amino acid transaminase 2 (BCAT2) inhibitor with IC50 of 54 nM. |
| PC-26620 |
BCAT2 inhibitor C10
BACT2 inhibitor
|
BCAT2 inhibitor C10 is a potent, selective branched-chain amino acid transaminase 2 (BCAT2) inhibitor with IC50 of 44 nM. |
| PC-26619 |
BCAT2-IN-2
BACT2 inhibitor
|
BCAT2-IN-2 is a potent, selective, in-vivo efficacious BCATm (BCAT2) inhibitor with pIC50 of 7.3, 100-fold selective for BCATm over BCATc. |
| PC-26618 |
BCAT2-IN-1
BACT2 inhibitor
|
BCAT2-IN-1 is a potent, selective, in-vivo efficacious BCATm (BCAT2) inhibitor with pIC50 of 7.3, 100-fold selective for BCATm over BCATc. |
