| Cat. No. |
Product Name |
Information |
| PC-25259 |
IPR-803
uPAR-uPA inhibitor
|
IPR-803 is a small molecule inhibitor of the uPAR·uPA protein-protein interaction, binds directly to uPAR with sub-micromolar affinity of 0.2 uM. |
| PC-25258 |
IPR-456
uPAR-uPA inhibitor
|
IPR-456 is a small molecule inhibitor of the uPAR·uPA protein-protein interaction, binds to uPAR with Kd of 310 nM, inhibits uPA binding to uPAR of breast MDA-MB-231 tumor cells with IC50 of 8 uM. |
| PC-25256 |
Profilin-1 inhibitor UP-6
Profilin-1 inhibitor
|
Profilin-1 inhibitor UP-6 is a specific small molecule inhibitor of actin-binding protein profilin-1 (Pfn1), inhibits Pfn1-actin interaction and shows potent anti-angiogenic activity in vitro and in vivo. |
| PC-25255 |
Pfn1-actin interaction inhibitor C74
Profilin-1 inhibitor
|
Pfn1-actin interaction inhibitor C74 is a specific small molecule inhibitor of profilin1 (Pfn1)-actin interaction, reduces RCC cell proliferation in vitro and tumor growth in vivo. |
| PC-25254 |
Pfn1-actin interaction inhibitor C2
Profilin-1 inhibitor
|
Pfn1-actin interaction inhibitor C2 is a specific small molecule inhibitor of profilin1 (Pfn1)-actin interaction, inhibits the angiogenic ability of vascular endothelial cells (ECs), affects the actin cytoskeleton, migration, and proliferation of Ecs. |
| PC-25253 |
Pfn1-actin interaction inhibitor C1
Profilin-1 inhibitor
|
Pfn1-actin interaction inhibitor C2 is a specific small molecule inhibitor of profilin1 (Pfn1)-actin interaction, inhibits the angiogenic ability of vascular endothelial cells (ECs), affects the actin cytoskeleton, migration, and proliferation of ECs. |
| PC-25248 |
FLIX5
EPLIN inhibitor
|
FLIX5 (NSC328403, 4-Formylcolchicine) is a specific small molecule targeting EPLIN (Epithelial Protein Lost In Neoplasm), binds stably to EPLIN and exhibits broad cytotoxicity against both neuroblastoma and medulloblastoma cells, primarily by triggering apoptosis. |
| PC-25235 |
Ofirnoflast
NEK7 inhibitor
|
Ofirnoflast (HT-6184) is first-in-class, allosteric and orally bioavailable NEK7 inhibitor that disrupts NEK7-NLRP3 protein interaction, thereby preventing the formation of the NLRP3 inflammasome. |
| PC-25234 |
(S)-Perillaldehyde
SRD5A1 inhibitor
|
(S)-Perillaldehyde (L-Perillaldehyde) is a major active monomer extracted from Perilla, shows antidepressant-like activity through the olfactory nervous function, also inhibits CRC by targeting SRD5A1, thereby promoting autophagy through the PI3K/AKT pathway. |
| PC-25229 |
Beta-aminopropionitrile
LOX inhibitor
|
Beta-Aminopropionitrile (BAPN, β-Aminopropionitrile) is an irreversible and orally active lysyl oxidase (LOX) inhibitor, targets the active site of LOX or LOXL isoenzymes. |
| PC-25223 |
AGPAT4 inhibitor CL26
AGPAT4 inhibitor
|
AGPAT4 inhibitor CL26 is a potent, isoform-specific, covalent inhibitor of acylglycerol-3-phosphate o-acyltransferase 4 (AGPAT4) inhibitor with IC50 of 795 nM, binds to Cys228 of AGPAT4. |
| PC-25219 |
Chlorogenic acid
CAS 327-97-9
|
Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb, is an orally active with antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension activities. |
