| Cat. No. |
Product Name |
Information |
| PC-26220 |
Thiostrepton
FOXM1 inhibitor
|
Thiostrepton is a thiazole antibiotic that selectively inhibits FOXM1, also significantly inhibits ETV4 K97-Khib, thereby promoting ferroptosis and suppressing ICC cell migration, invasion, and lung metastasis. |
| PC-26216 |
Furin inhibitor 9
Furin inhibitor
|
Furin inhibitor 9 is a highly potent, small molecule inhibitor of proprotein convertase (PC) furin with Ki of 12.4 nM, weakly inhibits the structurally related PC7 with Ki of 278 nM, shows antiviral potency against the furin-dependent H7N7 influenza A strain SC35M. |
| PC-26215 |
Furin inhibitor 27
Furin inhibitor
|
Furin inhibitor 27 is a highly potent, small molecule inhibitor of proprotein convertase (PC) furin with Ki of 1.67 nM, also inhibits the structurally related PC7 with Ki of 7.27 nM. |
| PC-26214 |
MI-1851
Furin inhibitor
|
MI-1851 is a highly potent, peptidic mimetic inhibitor of furin with Ki of 10.1 pM, inhibits SARS-CoV-2 replication. |
| PC-26213 |
GLO1 inhibitor 3d
Glyoxalase I inhibitor
|
GLO1 inhibitor 3d is a potent glyoxalase I (GLO1) inhibitor with IC50 of 11 nM. |
| PC-26207 |
DB1033
Oct1/OCA-B inhibitor
|
DB1033 is a small molecule inhibitor of Oct1/OCA-B transcription complexes, inhibits cellular OCA-B activity with IC50 of 26.1 uM, disrupts the interaction between Oct1 and OCA-B. |
| PC-26206 |
164B8
Pin1 degrader
|
164B8 is a highly potent, covalent Pin1 inhibitor / degrader with IC50 of 4.65 nM, reacts with the Pin1 active-site residue Cys113, effectively induces Pin1 degradation both in cell and in vivo. |
| PC-26205 |
CN-0928
PCBP2 inhibitor
|
CN-0928 is a specific small molecule inhibitor of poly(C)-binding protein 2 (PCBP2), mitigates AD pathology by inhibiting PCBP2 condensation. |
| PC-26190 |
4-Methylumbelliferone
Hyaluronan biosynthesis inhibitor
|
4-Methylumbelliferone (4-MU) is a plant-derived coumarin and specific small molecule inhibitor of hyaluronan biosynthesis hyaluronan-mediated motility receptor (HMMR), shows antitumoral and antimetastatic effects. |
| PC-26189 |
Gαi2 inhibitor GT-14
Gαi2 inhibitor
|
GT-14 is a first-generation small molecule inhibitor of Gαi2 protein, inhibits cancer cell migration and prevents Gαi2 activation. |
| PC-26185 |
Biliverdin
114-25-0
|
Biliverdin is a prototypical tetrapyrrolic chromophore compound and HO-1 metabolic product, mediates the protective effects of HO-1 in many disease models including IRI and organ transplantation, exhibits anti-mutagenic, an antioxidant, anti-inflammatory, and immunosuppressant properties. |
| PC-26184 |
WGU55
TMPRSS6 inhibitor
|
WGU55 is a potent, selective peptidomimetic TMPRSS6 inhibitor with Ki of 12.15 nM and IC50 of 138 nM in TMPRSS6-transfected HEK293 cells, shows >200-fold selectivity over matriptase, Factor Xa and Thrombin. |
