| Cat. No. |
Product Name |
Information |
| PC-23217 |
Steroid sulfatase inhibitor DU-14
Steroid sulfatase inhibitor
|
Steroid sulfatase inhibitor DU-14 is a hihly potent steroid sulfatase (STS) inhibitor with IC50 of 55.8 nM, inhibits inhibits the MCF-7 cell proliferation with IC50 of 38.7 nM. |
| PC-23216 |
hPIF1 inhibitor 6
PIF1 inhibitor
|
hPIF1 inhibitor 6 is a specific small molecule inhibitor targeting the helicase activity of human PIF1 with IC50 of 36 uM for inhibition of FLhPIF1 helicase activity, 22-fold selective over hUPF1, inhibits hPIF1 DNA-binding and helicase activity in vitro. |
| PC-23178 |
SCR-7952
MAT2A inhibitor
|
SCR-7952 is a potent, highly selective methionine adenosyltransferase 2A (MAT2A) inhibitor with IC50 of 18.7 nM, Ki of 14.49 nM, shows MTAP-null selective antiproliferative activity. |
| PC-23122 |
FUT8 Inhibitor 40
FUT8 inhibitor
|
FUT8 Inhibitor 40 (FUT8-IN-2) is a selective, cell-active inhibitor of α-1,6-fucosyltransferase (FUT8), inhibits FUT8 without inhibiting other FUTs. |
| PC-23069 |
QC-308
Heme oxygenase inhibitor
|
QC-308 is a potent heme oxygenase (HO) inhibitor witn IC50 of 0.27 uM and 0.46 uM for hHO-1 and hHO-2 respectively. |
| PC-23067 |
CDD-3290
PSA inhibitor
|
CDD-3290 (CDD3290) is a specific small molecule inhibitor of prostate-specific antigen (PSA; KLK3) with Ki of 216 nM. |
| PC-23025 |
GSDMD agonist DMB
Gasdermin D agonist
|
GSDMD agonist DMB is a direct and selective gasdermin D (GSDMD) agonist, activates GSDMD pore formation to trigger liposome leakage with EC50 of 0.7 uM, activates GSDMD pore formation and pyroptosis without cleaving GSDMD. |
| PC-23021 |
SRSF10 inhibitor 1C8
SRSF10 inhibitor
|
SRSF10 inhibitor 1C8 is a specific small molecule inhibitor of SRSF10, alters splicing regulation mediated by SRSF10, shows strong anti-HIV-1 potency against a variety of clinical strains in vitro. |
| PC-22980 |
Peptide SBT-20
ROS-lowering peptide
|
Peptide SBT-20 (SS-20) is a cell-permeable peptide targeting the inner mitochondrial membrane, reduces ROS, normalizes electron transport chain function and ATP generation. |
| PC-22860 |
GZ667161
Glucosylceramide synthase inhibitor
|
GZ667161 (Genz-667161) is potent, orally available and CNS-penetrant inhibitor of Glucosylceramide synthase (GCS), alleviates aberrations in synucleinopathy models. |
| PC-22844 |
LXG6403
LOX inhibitor
|
LXG6403 is a highly potent, irreversible lysyl oxidase (LOX) inhibitor, inhibits cellular LOX activity efficiently in MDA-MB-231 cells with IC50 of 1.3 uM, >3-fold selective over LOXL2 and no activity against LOXL1. |
| PC-22799 |
BCATc inhibitor 2
BCAT1 inhibitor
|
BCATc inhibitor 2 (Bi2) is a specific inhibitor of cytosolic branched-chain aminotransferase (BCATc, BCAT1) with IC50 of 0.2/ 0.8 uM for rat/human BCATc respectively, weakly inhibits rat mitochondrial isoenzyme rBCATm. |
