| Cat. No. |
Product Name |
Information |
| PC-24310 |
NFS1 inhibitor Compound 53
NFS1 inhibitor
|
NFS1 inhibitor Compound 53 is the first potent, selective inhibitor of human cysteine desulfurase (NFS1) with IC50 of 40.5 uM and Ki of 6.4 uM. |
| PC-24295 |
HOSU-53
DHODH inhibitor
|
HOSU-53 is a potent and selective inhibitor of DHODH with IC50 of 0.95 nM (hDHODH), exhibits potent antileukemic activity. |
| PC-24293 |
HypoxyStat
Hypoxia inducer
|
HypoxyStat is a small molecule that increase oxygen-hemoglobin binding affinity cause tissue hypoxia, binds hemoglobin, induces systemic hypoxia in mice breathing normoxic (21% O2) air. |
| PC-24282 |
BKT300
PRC1 inhibitor
|
BKT300 is a small molecule inhibitor of leukemic cell migration and survival by targeting the PRC1 pathways, efficiently and specifically binds protein regulator of cytokinesis 1 (PRC1) with SPR Kd of 28.3 nM. |
| PC-24261 |
SARM1 inhibitor NB-7
SARM1 inhibitor
|
SARM1 inhibitor NB-7 is a potent, selective and uncompetitive inhibitor of the nicotinamide adenine dinucleotide (NAD) hydrolase SARM1 with biochemical IC50 of 0.025 uM, and IC50 of 0.008 uM in SARM-induced cell-death rescue assays. |
| PC-24260 |
SARM1 inhibitor 7
SARM1 inhibitor
|
SARM1 inhibitor 7 is a potent, selective sterile alpha and TIR Motif Containing 1 (SARM1) inhibitor with biochemical IC50 of 0.3 uM (hSARM1). |
| PC-24247 |
ACUPA TFA
PSMA inhibitor
|
ACUPA TFA is a potent prostate-specific membrane antigen (PSMA, GCPII) antagonist with Ki of 44.3 nM. |
| PC-24246 |
ACUPA
PSMA inhibitor
|
ACUPA is a potent prostate-specific membrane antigen (PSMA, GCPII) antagonist with Ki of 44.3 nM. |
| PC-24245 |
Vitamin B5 calcium
GOLPH3L inhibitor
|
Vitamin B5 calcium (VB5) is a small molecule inhibitor of Golgi phosphoprotein 3 like (GOLPH3L) with Kd of 1.15 uM in ITC assays, effectively blocks the binding of GOLPH3L and STING, subsequently promoting STING-NLRP3-mediated pyroptosis after radiotherapy (RT). |
| PC-24238 |
hCES2A inhibitor 14n
hCES2A inhibitor
|
hCES2A inhibitor 14n is a potent, selective and covalent human carboxylesterase 2A (hCES2A) inhibitor with IC50 of 0.04 nM. |
| PC-24230 |
NSC167409
HMGB1 inhibitor, EV-A71 inhibitor
|
Glycyrrhizin (NSC167409, Glycyrrhizic acid) is a direct HMGB1(high mobility group box 1) inhibitor, also is a specific inhibitor of EV-A71, blocks EV-A71 replication both in vivo and in vitro. |
| PC-24222 |
I3MT-3
3MST inhibitor
|
I3MT-3 (HMPSNE, 3MST inhibitor 3) is a potent, selective, cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) with IC50 of 2.7 uM. |
