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Enexasogaol

Chemical Structure : Enexasogaol

CAS No.: 23513-13-5

Enexasogaol (6-Shogaol)

货号: PC-61375Not For Human Use, Lab Use Only.

Enexasogaol (6-Shogaol) is a pungent agent isolated from Zingiber officinale Roscoe, has been known to have anti-tumor and anti-inflammatory effects.

规格 价格 库存 数量
25 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Enexasogaol (6-Shogaol) is a pungent agent isolated from Zingiber officinale Roscoe, has been known to have anti-tumor and anti-inflammatory effects.
    Enexasogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ.
    Enexasogaol inhibits TNF-alpha mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes.
    Enexasogaol also induces apoptotic cell death of human hepatoma p53 mutant Mahlavu subline via an oxidative stress-mediated caspase-dependent mechanism.

    物理化学性质&存储条件

    分子量 276.376
    分子式 C17H24O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (4E)-1-(4-hydroxy-3-methoxyphenyl)dec-4-en-3-one

    参考文献

    1. Isa Y, et al. Biochem Biophys Res Commun. 2008 Aug 29;373(3):429-34.

    2. Pan MH, et al. Mol Nutr Food Res. 2008 May;52(5):527-37.

    3. Chen CY, et al. J Agric Food Chem. 2007 Feb 7;55(3):948-54.

    4. Han Q,et al. Oncotarget. 2017 Jun 27;8(26):42001-42006.

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