Dishevelled (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-49501	Compound 3289-8625 Dvl PDZ inhibitor	Compound 3289-8625 is a small molecule inhibitor of the PDZ domain of dishevelled (Dvl) with KD of 10.6 uM, competitively inhibits the Wnt signaling.
PC-49500	NPL-4011 Dvl1-PDZ inhibitor	NPL-4011 is a specific small molecule inhibitor of PDZ domain of human Dvl1 (Dvl1-PDZ) with KD vaule of 34.5 uM in NMR titration experiments.
PC-73380	KY19334 CXXC5-Dvl PPI	KY19334 is a specific small molecule inhibitor of CXXC5-Dishevelled (Dvl) protein-protein interaction (PPI), restores the Wnt/β-catenin signalling.
PC-63513	KY-02061 CXXC5-Dvl PPI	KY-02061 is a small-molecule inhibitor of Dishevelled-CXXC5 interaction with IC50 of 24 uM in vitro binding assay.
PC-63512	KY-02327 CXXC5-Dvl PPI	KY-02327 is an orally active, small molecule inhibitor of the Dishevelled (Dvl)-CXXC5 interaction with IC50 of 3.1 uM, a metabolically stabilized KY-02061 analog.
PC-61785	NSC 668036 Dvl1-PDZ inhibitor	NSC 668036 is a specific inhibitor of the Dishevelled (Dvl) PDZ domain, extremely weakly binds to PSD-95, PSD95, and PDZ7 domain of GRIP.
PC-20575	BMD4702 Dishevelled inhibitor	BMD4702 is a small molecule Dishevelled (Dvl) PDZ domain with binding Kd of 186 nM.
PC-20574	BMD4722 Dishevelled inhibitor	BMD4722 is a highly potent, small-molecule inhibitor of Dvl-CXXC5 interaction with IC50 of 2.59 uM, directly binds to the Dvl PDZ domain (Kd=22.3 uM).

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