| Cat. No. |
Product Name |
Information |
| PC-21291 |
TopBP1 inhibitor 5D4
TopBP1
|
TopBP1 inhibitor 5D4 is a small-molecule inhibitor of TopBP1 (topoisomerase IIβ-binding protein 1), specifically targets the BRCT7/8 domains of TopBP1, blocks MYC activity by freeing MIZ1, a MYC inhibitor, from TopBP1. |
| PC-20800 |
KI-MS2-008
Max homodimer stablizer
|
KI-MS2-008 is a small molecule Max binder that modulate Myc-driven transcription in cells (IC50=1.28 uM) and inhibit viable cell levels in a Myc-dependent manner. |
| PC-20799 |
NSC13728 hydrochloride
Myc-Max inhibitor
|
NSC13728 hydrochloride is a specific small molecule stabilizer of the Max homodimer inhibiting Myc function, also inhibits Myc-Max heterodimerization. |
| PC-20798 |
NSC13728
Myc-Max inhibitor
|
NSC13728 is a specific small molecule stabilizer of the Max homodimer inhibiting Myc function, also inhibits Myc-Max heterodimerization. |
| PC-49522 |
c-Myc inhibitor DJ34
c-Myc inhibitor
|
DJ34 is a novel compound that induces dual c-Myc depletion and p53 activation in a wide range of tumor cell types, DJ34 is a DNA intercalator and topoisomerase II inhibitor, interferes with c-Myc synthesis. |
| PC-49220 |
VPC-70063
c-Myc inhibitor
|
VPC-70063 (VPC70063) is a small molecule Myc inhibitor that inhibits Myc-Max transcriptional activity with IC50 of 8.9 uM in c-Myc luciferase reporter assay in LNCaP cells, disrupts the interaction of Myc-Max with DNA. |
| PC-47053 |
D089
Myc inhibitor
|
D089 is a selective small molecule stabilizer of the MYC G4-quadruplex, not only inhibits MYC expression in myeloma cell lines, but also selectively induces G1 arrest in MYC-driven cancer cell lines containing the MYC-G4 sequence. |
| PC-38695 |
MYRA-B
c-MYC inhibitor
|
MYRA-B (NSC45641) is a small molecule that induces Myc-dependent apoptosis without affecting Myc transactivation or Myc/Max DNA binding. |
| PC-38694 |
MYRA-A
c-MYC inhibitor
|
MYRA-A (NSC339585) is a small molecule Myc pathway response agent (MYRA) that inhibits Myc transactivation and interferes with the DNA-binding activity of Myc family proteins, with no effect on the E-box-binding protein USF. |
| PC-38693 |
KSI-3716
c-MYC inhibitor
|
KSI-3716 is a small molecule c-MYC inhibitor that blocks c-MYC/MAX binding to target gene promoters, inhibits c-MYC mediated transcriptional activity at concentrations as low as 1 uM. |
| PC-38661 |
L755507
c-Myc-MAX inhibitor
|
L755507 is a potent, selective β3-adrenoceptor (β3-AR) agonist, exhibits robust concentration-dependent increase in cAMP accumulation in CHO-K1 cells expressing human β3-adrenoceptors (pEC50=12.3), also effectively inhibits the c-Myc-MAX heterodimerization. |
| PC-38523 |
F1021-0686
c-Myc inhibitor
|
F1021-0686 is a novel small molecule inhibitor of c-Myc, causes the functional repression of c-Myc target gene, shows appreciable anticancer activity against c-Myc expressing cell lines (HT29, IC50=1.55 uM). |
