Cat. No. |
Product Name |
Information |
PC-49447 |
ZZL-7
SERT-nNOS inhibitor
|
ZZL-7 (Ac-Ala-Val-OMe) is a small molecule inhibitor of SERT-nNOS interaction, induces a fast-onset antidepressant effect by enhancing serotonin signaling in forebrain circuits. |
PC-49390 |
T1059
eNOS/iNOS inhibitor
|
T1059 is a selective inhibitor of eNOS/iNOS with a long-term vasoconstrictive effect in vivo. |
PC-47005 |
PCC-0105002
PSD95-nNOS inhibitor
|
PCC-0105002 is a novel small molecule inhibitor of PSD95-nNOS protein-protein interaction with IC50 of 1.4 uM. |
PC-35678 |
ZLc002
nNOS inhibitor
|
ZLc002 (ZLc-002) is a putative small-molecule inhibitor of nNOS interaction with NOS1AP, disrupts neuronal nitric oxide synthase-NOS1AP interaction in intact cells. |
PC-35420 |
3-Bromo-7-Nitroindazole
nNOS inhibitor
|
3-Bromo-7-Nitroindazole (3B7N) is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, is also potent against iNOS, inhibits rat nNOS, bovine eNOS, and rat iNOS with IC50 of 0.17, 0.86, and 0.29 uM. |
PC-35419 |
BYK191023 dihydrochloride
iNOS inhibitor
|
BYK191023 dihydrochloride (BYK-191023) is a potent, highly selective inhibitor of inducible nitric-oxide synthase (iNOS) with IC50 of 86 nM, >20-fold selectivity over nNOS and eNOS (IC50=17 and 162 uM). |
PC-35418 |
BYK191023
iNOS inhibitor
|
BYK191023 (BYK-191023) is a potent, highly selective inhibitor of inducible nitric-oxide synthase (iNOS) with IC50 of 86 nM, >20-fold selectivity over nNOS and eNOS (IC50=17 and 162 uM). |
PC-35193 |
CAT639
iNOS inhibitor
|
CAT639 is an improved analog of ATV399 that exhibits improved β-cell viability and insulin secretion in the rat insulin-producing INS1E cells and primary rat dispersed islet cells, inhibits dimerization of iNOS. |
PC-35192 |
ATV399
iNOS inhibitor
|
ATV399 (ATV-399) is a novel small molecule that dose-dependently reduces the cleaved caspase 9 levels with IC50 of 3.3 uM, inhibits dimerization of iNOS. |
PC-42897 |
GW274150
iNOS inhibitor
|
GW274150 is a potent and highly selective inhibitor of iNOS with IC50 of 1.4 uM, displays >200 fold selectivity over eNOS and nNOS (IC50>100 uM). |
PC-42371 |
SDMA
Nitric oxide synthase inhibitor
|
SDMA (Symmetric dimethylarginine) is an arginine derivative and an endogenous inhibitor of nitric oxide (NO) synthase activity. |
PC-62230 |
AR-C102222
iNOS inhibitor
|
AR-C102222 is a potent, selective iNOS inhibitor with IC50 of 35 nM, dislapys 3,000-fold and 20-fold selectivity over eNOS and nNOS respectively. |