3-Bromo-7-Nitroindazole (3B7N)

Chemical Structure : 3-Bromo-7-Nitroindazole

CAS No.: 74209-34-0

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货号: PC-35420Not For Human Use, Lab Use Only.

3-Bromo-7-Nitroindazole (3B7N) is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, is also potent against iNOS, inhibits rat nNOS, bovine eNOS, and rat iNOS with IC50 of 0.17, 0.86, and 0.29 uM.

规格	价格	库存
10 mg	￥380	In stock
25 mg	￥580	In stock
100 mg	￥1280	In stock
250 mg		Get quote

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生物&药学活性

3-Bromo-7-Nitroindazole (3B7N) is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, is also potent against iNOS, inhibits rat nNOS, bovine eNOS, and rat iNOS with IC50 of 0.17, 0.86, and 0.29 uM.

物理化学性质&存储条件

分子量	242.032
分子式	C7H4BrN3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-bromo-7-nitro-1H-indazole

参考文献

1. Gammie SC, et al. Brain Res. 2000 Jul 7;870(1-2):80-6.

2. Gocmez SS, et al. Pharmacol Biochem Behav. 2015 Apr;131:19-25.

3. Widdowson PS, et al. Br J Pharmacol. 1996 Apr;117(8):1761-7.

4. Vaupel DB, et al. Eur J Pharmacol. 1997 Apr 11;324(1):11-20.