| Cat. No. |
Product Name |
Information |
| PC-49584 |
BTT-877
Autotaxin inhibitor
|
BTT-877 (BTT877) is a potent, selective and orally active inhibitor of autotaxin (ENPP2) with in vitro and ex vivo IC50 of 2.4 nM and 6.89 nM, respectively. |
| PC-38743 |
ONO-8430506
Autotaxin inhibitor
|
ONO-8430506 is a highly potent, orally available autotaxin (ATX) inhibitor with IC50 of 10 nM (recombinant human ATX), exhibits LysoPLD inhibitory activity in human plasma with IC50 of 5.5 nM. |
| PC-38464 |
HA155
Autotaxin inhibitor
|
HA155 is a potent, boronic acid-based autotaxin (ATX) inhibitor with IC50 of 5.7 nM, also used for conjugation to icodextrin. |
| PC-73412 |
Cudetaxestat
Autotaxin inhibitor
|
Cudetaxestat (BLD-0409, PAT-409) is a potent, selective, noncompetitive autotaxin (NPP2/ATX) inhibitor with IC50 of 4.95 nM (ATX), shows potential for indication of pulmonary fibrosis. |
| PC-72882 |
Autotaxin-IN-13
Autotaxin inhibitor
|
Autotaxin-IN-13 ( ATX-i) is a highly potent, selective Autotaxin inhibitor with IC50 of 6 nM. |
| PC-72060 |
BIO-32546
Autotaxin inhibitor
|
BIO-32546 (BIO 32546) is a potent, selective, orally bioavailable, brain-penetrable Autotaxin inhibitor with IC50 of 1 nM. |
| PC-38008 |
CRT0273750
Autotaxin inhibitor
|
CRT0273750 (IOA-289) is a potent, seletive inhibitor of autotaxin with IC50 of 1 nM. |
| PC-35168 |
Autotaxin inhibitor 12
Autotaxin inhibitor
|
Autotaxin inhibitor 12 is a highly potent, selective, orally-bioavailable inhibitor of autotaxin with IC50 of 3.1 nM in choline release assays. |
| PC-43508 |
PF-8380
Autotaxin inhibitor
|
PF-8380 (PF8380) is a potent, specific, orally active Autotaxin inhibitor with IC50 of 2.8 and 101 nM in enzyme assay and in human whole blood assay, respectively. |
| PC-60695 |
Autotaxin inhibitor compound 1
Autotaxin inhibitor
|
Autotaxin inhibitor compound 1 (Autotaxin-IN-1) is a potent, selective, orally bioavailable inhibitor of Autotaxin with IC50 of 2.2 nM in ex vivo human whole blood assay, does not inhibit related proteins ENPP1 and ENPP7. |
| PC-60640 |
GWJ-A-23
Autotaxin inhibitor
|
GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound. |
| PC-60639 |
PAT-048
Autotaxin inhibitor
|
PAT-048 (PAT048) is a potent, selective, noncompetitive autotaxin inhibitor with IC50 of 1.1 nM against the lysoPLD activity of human ATX. |
