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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Autotaxin-HA155
HA155

Chemical Structure : HA155

CAS No.: 1229652-22-5

HA155 (Autotaxin Inhibitor IV)

货号: PC-38464Not For Human Use, Lab Use Only.

HA155 is a potent, boronic acid-based autotaxin (ATX) inhibitor with IC50 of 5.7 nM, also used for conjugation to icodextrin.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

HA155 is a potent, boronic acid-based autotaxin (ATX) inhibitor with IC50 of 5.7 nM, also used for conjugation to icodextrin.

物理化学性质&存储条件

分子量 463.286
分子式 C24H19BFNO5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

B-[4-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-boronic acid

参考文献

1. Albers HM, et al. J Med Chem. 2011 Jul 14;54(13):4619-26.

2. Fisher N, et al. J Med Chem. 2018 Sep 13;61(17):7942-7951.

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