| Cat. No. |
Product Name |
Information |
| PC-22191 |
Diclofenac
COX inhibitor
|
Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a cyclooxygenase (COX) inhibitor with IC50 of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells. |
| PC-20235 |
SC-58125
COX-2 inhibitor
|
SC-58125 is a potent, selective inhibitor of COX-2 with IC50 of 0.05 uM, without inhibition on COX-1 (IC50>10 uM). |
| PC-20195 |
Lumiracoxib
COX-2 inhibitor
|
Lumiracoxib (COX-189) is a highly selective COX-2 inhibitor with IC50 of 0.14 uM in COX-2-expressing dermal fibroblasts, inhibits purified COX-2 with Ki of 0.06 uM, 50-fold selectivity over COX-1 (Ki=3 uM). |
| PC-63183 |
Robenacoxib
Cyclooxygenase inhibitor
|
Robenacoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in veterinary medicine for the relief of pain and inflammation in cats and dogs, a Cyclooxygenase(COX)-1 and COX-2 inhibitor.. |
| PC-63065 |
Polmacoxib
COX-2 inhibitor
|
Polmacoxib (CG-100649) is a novel NSAID proposed to inhibit both COX-2 and carbonic anhydrase (CA)-I/-II. |
| PC-62969 |
NCX-4016
COX-1 inhibitor
|
NCX-4016 (Nitroaspirin, NO-Aspirin 1) is a nitroderivative of aspirin that combines cyclooxygenase inhibitor with an NO donor, directly and irreversiblely inhibits COX-1. |
| PC-62881 |
Chemocoxib A
COX-2 inhibitor
|
Chemocoxib A is a highly potent, selective, cytotoxic COX-2 inhibitor with IC50 of 290 nM and 90 nM for wt mCOX-2 and R120Q COX-2 mutant respectively. |
| PC-62672 |
Tilmacoxib
COX-2 inhibitor
|
Tilmacoxib (JTE-522) is a potent, selective inhibitor of cyclooxygenase-2 (COX-2) that inhibits human recombinant COX-2 with IC50 of 85 nM, dispalys no activity against COX-1 (IC50>100 uM). |
| PC-62501 |
PTUPB
AKR1C3 inhibitor, COX-2/sEH inhibitor
|
PTUPB is a novel dual acting COX-2/sEH inhibitor with IC50 of 1.26 uM/0.9 nM, also is a potent AKR1C3 inhibitor with IC50 of 65 nM. |
| PC-61664 |
SC-236
COX-2 inhibitor
|
SC-236 (SC58236) is a potent, selective, orally active inhibitor of COX-2 with IC50 of 10 nM. |
| PC-61415 |
Vitacoxib
COX-2 inhibitor
|
Vitacoxib is a potent, selective COX-2 inhibitor with IC50 of 0.34 ug/mL, >50-fold selectivity over COX-1 (IC50=19.4 ug/mL). |
| PC-60430 |
ASP-6537
COX-1 inhibitor
|
ASP-6537 (FK 881, FR 122047) is a novel potent, selective, reversible cyclooxygenase-1 (COX-1) inhibitor with IC50 of 4.9 nM. |
