CXT29 | COX-2 inhibitor/TP antagonist | Probechem Biochemicals

Chemical Structure : CXT29

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CXT29 (CXT-29)

货号: PC-28609Not For Human Use, Lab Use Only.

CXT29 is a potent, dual inhibitor of cyclooxygenase (COX) and thromboxane receptor (TP receptor) antagonist with IC50 of 13 nM/772 nM for COX-2/COX-1, inhibits platelet aggregation with IC50 of 96 nM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

CXT29 is a potent, dual inhibitor of cyclooxygenase (COX) and thromboxane receptor (TP receptor) antagonist with IC50 of 13 nM/772 nM for COX-2/COX-1, inhibits platelet aggregation with IC50 of 96 nM.
CXT29 suppresses TXA2-dependent platelet aggregation and inflammatory pain in mice after oral administration at 50 mg/kg.

物理化学性质&存储条件

分子量	367.42
分子式	C22H22FNO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(8-benzyl-1-ethyl-6-fluoro-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid

参考文献

1. Blua F, et al. J Med Chem. 2025 Nov 13;68(21):23185-23219.

CXT29 (CXT-29)

生物&药学活性

物理化学性质&存储条件

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CXT29 (CXT-29)

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物理化学性质&存储条件

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