Acetyl-CoA Carboxylase (ACC) (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-20376	ND-646 Acetyl-CoA carboxylase inhibitor	ND-646 (ND646) is a potent, selective and allosteric inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 of 3.5 and 4.2 nM for hACC1 and hACC2, respectively.
PC-73298	ACC2 inhibitor 2e ACC2 inhibitor	ACC2 inhibitor 2e is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 1.9 nM and 1950 nM for ACC2 and ACC1, respectively.
PC-73297	A-908292 ACC2 inhibitor	A-908292 is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 38 nM (hACC2), no activity against ACC1 (IC50>30 uM).
PC-72818	IMA-1 ALOX12 inhibitor	IMA-1 (ALOX12-ACC1 inhibitor IMA-1) is a small molecule that interrupt the arachidonate 12-lipoxygenase (ALOX12)-acetyl-CoA carboxylase 1 (ACC1) interaction.
PC-72388	PF-05221304 ACC inhibitor	PF-05221304 (PF 05221304) is a novel potent, selective, liver-targeted dual acetyl-CoA carboxylase (ACC1/2) inhibitor with IC50 of 13/9 nM (hACC1/2).
PC-72105	ACC1 inhibitor Compound 1 ACC1 inhibitor	ACC1 inhibitor Compound 1 is a potent, highly selective, oral ACC1 inhibitor with IC50 of 0.58 nM (hACC1), no effect on hACC2 (IC50>10 uM).
PC-36170	ND-654 Acetyl-CoA carboxylase inhibitor	ND-654 (ND654) is a novel potent, liver-specific acetyl-CoA carboxylase (ACC) inhibitor with IC50 of 3/8 nM for human ACC1/ACC2, respectively.
PC-63466	PF-05175157	PF-05175157 (PF-5175157) is a potennt Acetyl-CoA carboxylase (ACC) inhibitor with IC50 of 27 and 33 nM for hAAC1 and hACC2, respectively.
PC-61377	Firsocostat Acetyl-CoA carboxylase inhibitor	Firsocostat (ND-630, NDI-010976, GS-0976) is a highly potent, selective inhibitor of acetyl-CoA carboxylase (ACC) with IC50 of 2.1 and 6.1 nM for isozymes ACC1 and ACC2, respectively.
PC-61204	MK-4074 Acetyl-CoA carboxylase inhibitor	MK-4074 is a potent, liver-specific, orally active inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 of ~3 nM.
PC-42306	TOFA Acetyl-CoA carboxylase inhibitor	TOFA (RMI14514, MDL14514) is an indirect, allosteric inhibitor of Acetyl-CoA carboxylase-α (ACCA) and fatty acid synthesis.
PC-45395	Olumacostat glasaretil ACC inhibitor	Olumacostat glasaretil (DRM01) is a small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC).

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