| Cat. No. |
Product Name |
Information |
| PC-21190 |
Bestatin
CD13 inhibitor
|
Ubenimex (Bestatin) is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor with anticancer effects. |
| PC-49177 |
BDM88951
ERAP2 inhibitor
|
BDM88951 (BDM 88951) is a highly potent, selective inhibitor of endoplasmic reticulum aminopeptidase 2 (ERAP2) with IC50 of 19 nM. |
| PC-73107 |
M8891
MetAP-2 inhibitor
|
M8891 (M 8891) is an orally bioavailable, potent, and reversible methionine aminopeptidase 2 (MetAP2) inhibitor with IC50 of 54 nM, Ki of 4.33 nM. |
| PC-72623 |
ST-115
Aminopeptidase P2 inhibitor
|
ST-115 (ST115) is a potent and specific inhibitor of aminopeptidase P2 ((XPNPEP2, APP2) with IC50 of 3.7 nM. |
| PC-72273 |
IRAP-IN-1
IRAP inhibitor
|
IRAP-IN-1 is a selective insulin-regulated aminopeptidase (IRAP) inhibitor with IC50 of 32 nM, >25-fold selectivity over ERAP1 and ERAP2. |
| PC-72271 |
DG013A
ERAP1 inhibitor
|
DG013A (DG 013A) is tripeptide mimetic chemical probe (inhibitor) of ERAP1 with IC50 of 0.19 uM, 15-fold selectivity over ERAP2, potently inhibits aminopeptidase N (APN) with IC50 of 3.7 nM. |
| PC-38334 |
CARD8 activator CQ31
PEPD/XPNPEP1 inhibitor
|
CARD8 activator CQ31 is a small molecule that selectively activates CARD8, inhibits the M24B aminopeptidases prolidase (PEPD) and Xaa-Pro aminopeptidase 1 (XPNPEP1), leading to the accumulation of proline-containing peptides that inhibit DPP8/9 and thereby activate CARD8. |
| PC-35112 |
TP-004
MetAP-2 inhibitor
|
TP-004 is a potent, selective and reversible inhibitor of methionine aminopeptidase 2 (MetAP2) with IC50 of 6 nM. |
| PC-63347 |
A-800141
MetAP2 inhibitor
|
A-800141 is a potent, highly specific, orally bioavailable MetAP2 inhibitor with IC50 of 12 nM, shows no inhibition for MetAP1 (IC50>30 uM). |
| PC-63319 |
PPI-2458
MetAP-2 inhibitor
|
PPI-2458 is potent, specific, irreversible methionine aminopeptidase-2 (MetAP-2) inhibitor with IC50 of 0.2 nM, inhibits growth inhibition of HFLS-RA and HUVEC with IC50 of 0.04 nM. |
| PC-63318 |
A-357300
MetAP2 inhibitor
|
A-357300 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 0.12 uM, does not inhibit MetAP1 or leucine aminopeptidases at 10 uM. |
| PC-63317 |
A-832234
MetAP-2 inhibitor
|
A-832234 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 19 nM.. |
