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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI4K

Request The Product List ofPI4K PI4K

Cat. No. Product Name Information
PC-49466

GSK-3923868

PI4KB inhibitor

GSK-3923868 (PI4KB inhibitor 30) is a potent, selective, slow-dissociating PI4KB (PI4kIII-beta) inhibitor with pKi of 9.8, >1000-fold selectivity over PI4KA, inhibits HRV viral replication in COPD BECs.
PC-73080

AZ3

PI4KB inhibitor

AZ3 (PI4KB inhibitor 3) is a seletive PI4KB inhibitor with pIC50 of 7.8, shows good lipid kinase selectivity (pIC50 5.1, 4.7 and 4.0 for PI4Kα, PI3Kα and PIP5Kγ respectively).
PC-73079

AZ7

PI4KA inhibitor

AZ7 (PI4KA inhibitor 7) is a potent, selective PI4KA inhibitor with pIC50 of 8.2, >100-fold selectivity over PI4Kβ, PI3Kα and PIP5Kγ.
PC-73078

Pipinib

PI4KB inhibitor

Pipinib is a small molecule Hedgehog signaling inhibitior by selective inhibition of phosphatidylinositol 4-kinase IIIβ (PI4KB, IC50=2.2 uM), inhibits Purmorphamine-induced osteogenesis with IC50 of 0.6 uM.
PC-35292

UCT943

PI4K inhibitor

UCT943 (UCT-943) is a potent, selective, next generation Plasmodium falciparum PI4K inhibitor with IC50 of 23 nM.
PC-35278

UCB9608

PI4KIIIβ inhibitor

UCB9608 (UCB-9608) is a potent, selective, orally bioavailable PI4KIIIβ inhibitor with IC50 of 11 nM.
PC-35202

GSK-A1

PI4KA inhibitor

PI4KA inhibitor A1 (GSK-A1) is a highly specific and potent inhibitor of Phosphatidylinositol 4-kinase IIIα (PI4KIIIα).
PC-63343

T-00127-HEV1

PI4KB inhibitor

T-00127-HEV1 is a broad-spectrum antienterovirus compound that selectively inhibits PI4KB activity with IC50 of 60 nM, inhibits poliovirus pseudovirus and EV71 in RD cells with IC50 of 0.77 and 0.73 uM.
PC-63342

AL-9

PI4KIIIα inhibitor

AL-9 is a small molecule HCV replication inhibitor with EC50 of 0.29 and 0.75 uM for genotype 1b and 2a, inhibits purified PI4KIIIα with IC50 of 0.57 uM.
PC-63341

BF738735

PI4KB inhibitor

BF738735 is a novel, broad-spectrum inhibitor of enterovirus replication (EC50=4-71 nM) that specifically targets host cell factor PI4KIIIβ with IC50 of 5.7 nM, 300-fold less potent for PI4KIIIα (IC50=1.7 uM).
PC-42861

PIK-93

PI4K inhibitor

PIK-93 is a potent, synthetic PI4K inhibitor with IC50 of 19 nM (PI4KIIIβ), also inhibits PI3Kγ and PI3Kα with IC50 of 16 nM and 39 nM, respectively.
PC-61696

KDU691

PI4K inhibitor

KDU691 is a potent, selective, orally active parasite PI4K inhibitor with IC50 of 1.5 nM for P. vivax PI4K (PvPI4K).

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