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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI4K-AZ3
AZ3

Chemical Structure : AZ3

CAS No.: 1608501-57-0

AZ3 (PI4KB inhibitor 3)

货号: PC-73080Not For Human Use, Lab Use Only.

AZ3 (PI4KB inhibitor 3) is a seletive PI4KB inhibitor with pIC50 of 7.8, shows good lipid kinase selectivity (pIC50 5.1, 4.7 and 4.0 for PI4Kα, PI3Kα and PIP5Kγ respectively).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    AZ3 (PI4KB inhibitor 3) is a seletive PI4KB inhibitor with pIC50 of 7.8, shows good lipid kinase selectivity (pIC50 5.1, 4.7 and 4.0 for PI4Kα, PI3Kα and PIP5Kγ respectively).

    物理化学性质&存储条件

    分子量 499.604
    分子式 C23H25N5O4S2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-1-acetyl-N-(4-methyl-5-(6-(phenylsulfonamido)pyridin-2-yl)thiazol-2-yl)piperidine-2-carboxamide

    参考文献

    1. Michael J Waring, et al. Chem Commun (Camb). 2014 May 25;50(40):5388-90.

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