T-00127-HEV1 | PI4KB inhibitor | Probechem Biochemicals

Chemical Structure : T-00127-HEV1

CAS No.: 900874-91-1

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T-00127-HEV1 (PI4KB inhibitor)

货号: PC-63343Not For Human Use, Lab Use Only.

T-00127-HEV1 is a broad-spectrum antienterovirus compound that selectively inhibits PI4KB activity with IC50 of 60 nM, inhibits poliovirus pseudovirus and EV71 in RD cells with IC50 of 0.77 and 0.73 uM.

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5 mg	￥1380	In stock
10 mg	￥2180	In stock
25 mg	￥3580	In stock
50 mg	￥5580	In stock
100 mg		Get quote

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生物&药学活性

T-00127-HEV1 is a broad-spectrum antienterovirus compound that selectively inhibits PI4KB activity with IC50 of 60 nM, inhibits poliovirus pseudovirus and EV71 in RD cells with IC50 of 0.77 and 0.73 uM.
T-00127-HEV1 shows a moderate inhibitory effect on PIK3CD activity, and high selectivity over other PI kinases.
T-00127-HEV1 demonstrates antipoliovirus activity ,does not inhibit hepatitis C virus (HCV) replication.

物理化学性质&存储条件

分子量	411.506
分子式	C22H29N5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(3,4-dimethoxyphenyl)-2,5-dimethyl-N-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidin-7-amine

参考文献

1. Arita M, et al. J Virol. 2011 Mar;85(5):2364-72.

T-00127-HEV1 (PI4KB inhibitor)

生物&药学活性

物理化学性质&存储条件

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T-00127-HEV1 (PI4KB inhibitor)

生物&药学活性

物理化学性质&存储条件

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