AL-9 | PI4KIIIα inhibitor | Probechem Biochemicals

Chemical Structure : AL-9

加入收藏

AL-9 (HCV inhibitor AL-9)

货号: PC-63342Not For Human Use, Lab Use Only.

AL-9 is a small molecule HCV replication inhibitor with EC50 of 0.29 and 0.75 uM for genotype 1b and 2a, inhibits purified PI4KIIIα with IC50 of 0.57 uM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

AL-9 is a small molecule HCV replication inhibitor with EC50 of 0.29 and 0.75 uM for genotype 1b and 2a, inhibits purified PI4KIIIα with IC50 of 0.57 uM.
AL-9 inhibits HCV across different genotypes with activity in the sub-micromolar to low micromolar range in the absence of significant cytotoxic effects.
AL-9 inhibits PI4KIIIα also in living cells, while not appreciably affecting the activity of PI4KIIIβ, does not affect the level of PI4P in the Golgi membrane.

物理化学性质&存储条件

分子量	402.454
分子式	C23H22N4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(5-(4-((4-morpholinophenyl)amino)quinazolin-6-yl)furan-2-yl)methanol

参考文献

1. Bianco A, et al. PLoS Pathog. 2012;8(3):e1002576.

2. MacLeod AM, et al. ACS Med Chem Lett. 2013 May 8;4(7):585-9.

AL-9 (HCV inhibitor AL-9)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

AL-9 (HCV inhibitor AL-9)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.