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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI4K-GSK-3923868
GSK-3923868

Chemical Structure : GSK-3923868

CAS No.: 2365241-79-6

GSK-3923868 (PI4KB inhibitor 30)

货号: PC-49466Not For Human Use, Lab Use Only.

GSK-3923868 (PI4KB inhibitor 30) is a potent, selective, slow-dissociating PI4KB (PI4kIII-beta) inhibitor with pKi of 9.8, >1000-fold selectivity over PI4KA, inhibits HRV viral replication in COPD BECs.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

GSK-3923868 (PI4KB inhibitor 30) is a potent, selective, slow-dissociating PI4KB (PI4kIII-beta) inhibitor with pKi of 9.8, >1000-fold selectivity over PI4KA, inhibits HRV viral replication in COPD BECs.

物理化学性质&存储条件

分子量 581.721
分子式 C33H39N7O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-(1-hydroxypropan-2-yl)-5-(5-(2-hydroxypropan-2-yl)-2-methyl-7-((3-(1-methyl-1H-imidazol-2-yl)benzyl)amino)pyrazolo[1,5-a]pyrimidin-3-yl)-N,2-dimethylbenzamide

参考文献

1. Patent WO2019141694 A1

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