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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aminopeptidase-BDM_92499
BDM_92499

Chemical Structure : BDM_92499

CAS No.:

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BDM_92499 (BDM-92499, BDM92499)

货号: PC-23920Not For Human Use, Lab Use Only.

BDM_92499 is a potent, selective inhibitor of insulin-regulated aminopeptidase IRAP with IC50 of 3.4 nM has >150-fold selecive\ity over ERAP1 and ARAP2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BDM_92499 is a potent, selective inhibitor of insulin-regulated aminopeptidase IRAP with IC50 of 3.4 nM has >150-fold selecive\ity over ERAP1 and ARAP2.

物理化学性质&存储条件

分子量 466.54
分子式 C25H30N4O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[(1S)-2-Amino-1-[(5-benzyloxy-1H-indol-3-yl)methyl]-2-oxo-ethyl]-2-(hydroxycarbamoyl)-4-methyl-pentanamide

参考文献

1. He B, et al. J Med Chem. 2025 Feb 7. doi: 10.1021/acs.jmedchem.4c01744.

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