| PC-22190 |
Ibuprofen
COX-1 inhibitor
|
Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective cyclooxygenase-1 (COX-1) inhibitor with IC50 value of 13 μM, inhibits cell proliferation, angiogenesis, and induces cell apoptosis, is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. |