GWJ-A-23 |CAS:1351930-95-4 Probechem Biochemicals

Chemical Structure : GWJ-A-23

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GWJ-A-23 (GWJ-23;GWJ23)

货号: PC-60640Not For Human Use, Lab Use Only.

GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound.

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生物&药学活性

GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound。
GWJ-A-23 reduces lung collagen, bronchoalveolar lavage cell counts, total protein, LPA, and TGF-β levels。
GWJ-A-23 attenuates the pathogenesis of pulmonary fibrosis in vivo.

物理化学性质&存储条件

分子量	385.14
分子式	C17H28NO4P
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(decanoylamino)benzyl]phosphonic acid

参考文献

1. Jiang G, et al. Bioorg Med Chem Lett. 2011 Sep 1;21(17):5098-101.

GWJ-A-23 (GWJ-23;GWJ23)

生物&药学活性

物理化学性质&存储条件

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GWJ-A-23 (GWJ-23;GWJ23)

生物&药学活性

物理化学性质&存储条件

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