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Autotaxin-IN-13

Chemical Structure : Autotaxin-IN-13

CAS No.: 1588501-59-0

Autotaxin-IN-13 (ATX-i)

货号: PC-72882Not For Human Use, Lab Use Only.

Autotaxin-IN-13 ( ATX-i) is a highly potent, selective Autotaxin inhibitor with IC50 of 6 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Autotaxin-IN-13 ( ATX-i) is a highly potent, selective Autotaxin inhibitor with IC50 of 6 nM.
    Autotaxin showed sufficient oral bioavailability and low plasma clearance in vivo as well as a suitable half-life to allow for bid or food admix dosing.

    物理化学性质&存储条件

    分子量 475.428
    分子式 C22H20F3N5O4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-(trifluoromethoxy)benzyl (3aS,6aS)-5-(1H-benzo[d][1,2,3]triazole-5-carbonyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

    参考文献

    1. Daniel Hunziker, et al. Front Pharmacol. 2022 Jan 18;12:699535.

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