2-Iminobiotin (2-IB, Guanidinobiotin)

Chemical Structure : 2-Iminobiotin

CAS No.: 13395-35-2

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货号: PC-28056Not For Human Use, Lab Use Only.

2-Iminobiotin (2-IB, Guanidinobiotin) is a biotin analog with neuroprotective properties, is a selective, reversible inhibitor of neuronal and inducible nitric oxide synthase (nNOS/iNOS) with Ki of 21.8 and 37.5 uM for murine iNOS and rat n-cNOS.

规格	价格	库存
25 mg	￥780	In stock
50 mg	￥1280	In stock
100 mg	￥1980	In stock
250 mg		Get quote
1 g		Get quote

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2-Iminobiotin (2-IB, Guanidinobiotin) is a biotin analog with neuroprotective properties, is a selective, reversible inhibitor of neuronal and inducible nitric oxide synthase (nNOS/iNOS) with Ki of 21.8 and 37.5 uM for murine iNOS and rat n-cNOS.

物理化学性质&存储条件

分子量	243.33
分子式	C10H17N3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-((3aR,6S,6aS)-2-Amino-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl)pentanoic acid

参考文献

1. Sup SJ, et al. Biochem Biophys Res Commun. 1994 Oct 28;204(2):962-8.

2. Utkan T, et al. Pharmacol Biochem Behav. 2012 Jun;101(4):515-9.

3. Peeters-Scholte C, et al. PLoS One. 2023 Sep 25;18(9):e0291915.

4. Peeters-Scholte C, et al. Stroke. 2002 Sep;33(9):2304-10.