BMD4722 | Dishevelled inhibitor | Probechem Biochemicals

Chemical Structure : BMD4722

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BMD4722 (BMD 4722)

货号: PC-20574Not For Human Use, Lab Use Only.

BMD4722 is a highly potent, small-molecule inhibitor of Dvl-CXXC5 interaction with IC50 of 2.59 uM, directly binds to the Dvl PDZ domain (Kd=22.3 uM).

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生物&药学活性

BMD4722 is a highly potent, small-molecule inhibitor of Dvl-CXXC5 interaction with IC50 of 2.59 uM, directly binds to the Dvl PDZ domain (Kd=22.3 uM).
BMD4722 effectively disrupted the interaction between Dvl PDZ domain and the DBM peptide in competitive Dvl-CXXC5 binding assays.

物理化学性质&存储条件

分子量	594.50
分子式	C31H32BrNO6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(O)CN1C2=C(C(CCC2)=O)C(C3=CC(OCC)=C(OCC4=CC=C(C)C=C4)C(Br)=C3)C5=C1CCCC5=O

参考文献

1. Songling Ma, et al. J Comput Aided Mol Des. 2018 May;32(5):643-655.

BMD4722 (BMD 4722)

生物&药学活性

物理化学性质&存储条件

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BMD4722 (BMD 4722)

生物&药学活性

物理化学性质&存储条件

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