欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Dishevelled-KY19334
KY19334

Chemical Structure : KY19334

CAS No.: 2319609-67-9

加入收藏

KY19334 (KY 19334)

货号: PC-73380Not For Human Use, Lab Use Only.

KY19334 is a specific small molecule inhibitor of CXXC5-Dishevelled (Dvl) protein-protein interaction (PPI), restores the Wnt/β-catenin signalling.

规格 价格 库存 数量
50 mg Get quote
100 mg Get quote
250 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    KY19334 is a specific small molecule inhibitor of CXXC5-Dishevelled (Dvl) protein-protein interaction (PPI), restores the Wnt/β-catenin signalling.
    KY19334 reverses obesity‐related metabolic diseases with adult tissue remodelling.
    Oral administration of KY19334 (25 mg/kg) suppressed fasting glucose levels improves obesity‐related insulin resistance with long‐lasting effect in HFD‐fed mice.
    KY19334 treatment improves hepatic glucose homeostasis. KY19334 enhances energy expenditure by increasing the thermogenic activity of beige‐fat tissues.
    KY19334 treatment restores β‐cell mass and functions in HFD‐fed and STZ‐induced diabetes mellitus (DM) mice.

    物理化学性质&存储条件

    分子量 307.309
    分子式 C17H13N3O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (2Z,3E)-3-(hydroxyimino)-5'-methoxy-[2,3'-biindolinylidene]-2'-one

    参考文献

    1. Seo SH, et al. Clin Transl Med. 2022 Apr;12(4):e742.

    备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    联系我们 sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    询单

    • *产品名称:
    • *姓名:
    • *邮箱:
    • *公司名称:
    • *询单数量:
    • *国籍:
    • 询单信息: