| Cat. No. |
Product Name |
Information |
| PC-20827 |
DFTD
eEF-2K inhibitor
|
DFTD is a time-dependent, reversible and covalent inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K) targeting of Cys-146, DFTD binds to the ATP binding site of eEF-2K. |
| PC-20814 |
Legumain inhibitor 7r
Legumain inhibitor
|
Legumain inhibitor 7r is a highly potent Legumain (asparagine endopeptidase, AEP) inhibitor with IC50 of 0.9 nM. |
| PC-20813 |
Legumain inhibitor 10t
Legumain inhibitor
|
Legumain inhibitor 10t is a potent, selective and cellularly active Legumain (asparagine endopeptidase, AEP) inhibitor with IC50 of 71 nM. |
| PC-20812 |
Legumain inhibitor 38u
Legumain inhibitor
|
Legumain inhibitor 38u is a selective inhibitor of asparagine endopeptidase (AEP, Legumain) with IC50 of 160 nM, inhibits cancer metastasis. |
| PC-20808 |
L524-0366
FN14 inhibitor
|
L524-0366 is a small-molecule inhibitor of Fn14, binds specifically to the Fn14 receptor and disrupts TWEAK-Fn14 interaction. |
| PC-20794 |
CK147
Sec61 inhibitor
|
CK147 (CK-147) is a potent CD4 down-modulator with IC50 of 63 nM, inhibits Sec61-dependent cotranslational translocation of huCD4 in vitro. |
| PC-20790 |
GO-203
MUC1-C inhibitor
|
GO-203 (GO203) is a cell-penetrating peptide inhibitor of mucin-1-cycloplasmic C-terminal subunit (MUC1-C), blocks homodimerization of the MUC1-C subunit required for nuclear translocation and downstream signaling. |
| PC-20782 |
Piericidin A
Complex I inhibitor
|
Piericidin A is a natural insecticide isolated from the spore forming bacterium Streptomyces mobaraensis, Piericidin A is a mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. |
| PC-20780 |
DX3-234
OXPHOS inhibitor
|
DX3-234 is a potent selective complex I oxidative phosphorylation (OXPHOS) inhibitor with IC50 of 42.6 nM in NAD+/NADH assay and IC50 of 29 nM in ATP depletion assay using MIA PaCa-2 cells. |
| PC-20764 |
SW088799
Glucagon release inhibitor
|
SW088799 is a small molecule glucagon release inhibitor with IC50 of 1.26 uM, with minimal impact on insulin release. |
| PC-20754 |
BACH1 inhibitor M2
Bach1 inhibitor
|
BACH1 inhibitor M2 is a small molecule inhibitor of the transcription factor BTB and CNC homolog 1 (BACH1), inhibits AFB1-induced porcine and human cell death in vitro and AFB1-induced symptoms of weight loss and liver injury in vivo. |
| PC-20751 |
FSHR agonist 21f
FSHR agonist
|
FSHR agonist 21f is a small molecule allosteric agonist of follicle stimulating hormone receptor (FSHR) with high affinity and activation efficacy (pEC50=7.72). |
