| Cat. No. |
Product Name |
Information |
| PC-28366 |
MMS-350
Antifibrotic
|
MMS-350 is a DMSO analog and bis-oxetanyl sulfoxide that acts as a radiation protector and mitigator, reduces pulmonary fibrosis induced by different triggers, reduces levels of extracellular matrix proteins, the activation of fibroblasts, and the induction of pro-fibrotic factors. |
| PC-28360 |
XJB-5-131
Antioxidant
|
XJB-5-131 is hemigramicidin-TEMPO conjugate and mitochondria-targeted ROS and electron scavenger, reduces apoptosis and enhances cell survival in mouse embryonic cells in vitro, improves mitochondrial function. |
| PC-28349 |
Herbacetin
Ornithine decarboxylase inhibitor
|
Herbacetin is a naturally occurring flavonoid and potent, specific, allosteric ornithine decarboxylase (ODC) inhibitor, exhibits potent anticancer activity in colon cancer cell lines expressing high levels of ODC. |
| PC-28332 |
PANK-IN-3
PANK3 inhibitor
|
PANK-IN-3 is a high-affinity, selective inhibitor of PANK3 (Pantothenate kinase 3) with Ki of 4.2 nM, 104-fold selective over PanK1β. |
| PC-28331 |
PANK-IN-2
PANK inhibitor
|
PANK-IN-2 is a poten tinhibitor of Pantothenate kinase (PANK) with IC50 of 92 nM for PanK2, 70 nM for PanK1β, and 25 nM for PanK3 respectively in radiochemical enzyme assays. |
| PC-28330 |
PANK-IN-1
PANK3 inhibitor
|
PANK-IN-1 is a potent, pantothenate competitive inhibitor of Pantothenate kinase (PANK) with IC50 of 0.51 uM against PANK3. |
| PC-28291 |
Racemetirosine
Tyrosine hydroxylase inhibitor
|
Racemetirosine (Alpha-methyltyrosine, alphaMT, Alpha-methyl-para-tyrosine) is a competitive small molecule tyrosine hydroxylase inhibitor, inhibits catecholamine biosynthesis, blocks hydroxylation of tyrosine into dihydroxyphenylalanine (DOPA). |
| PC-28249 |
SARM1 inhibitor B339
SARM1 inhibitor
|
SARM1 inhibitor B339 is a potent SARM1 inhibitor with IC50 of 7.215 uM, shows potential in prevention of axonal degeneration. |
| PC-28230 |
NSC 65828 sodium
Angiogenin inhibitor
|
NSC 65828 sodium (NCI-65828) is a small-molecule inhibitor of the ribonucleolytic activity of human angiogenin with Ki of 81 uM; possess antitumor activity in mice. |
| PC-28145 |
FM029
FOXP3-T-bet stabliezer
|
FM029 is a direct FOXP3 targeting small molecule that binds to FOXP3 (SPR KD=1.13 uM), stabilizes the FOXP3-T-bet interaction to represses T-bet-driven IFN-γ production. |
| PC-28105 |
SEP-227900
DAAO inhibitor
|
SEP-227900 is an orally active small molecule D-amino-acid oxidase (DAAO) inhibitor. |
| PC-28104 |
AS057278
DAAO inhibitor
|
AS057278 (MPCA, U-19425) is a potent, selective, orally active and blood-brain barrier (BBB) penetrant D-amino acid oxidase (DAAO) inhibitor with IC50 of 0.91 uM, shows potential anti-psychotic properties, also inhibits adipocyte lipolysis. |
