| Cat. No. |
Product Name |
Information |
| PC-23404 |
NAC1 inhibitor NIC3
NAC1 inhibitor
|
NAC1 inhibitor NIC3 is a specific small molecule inhibitor of oncogenic nucleus accumbens-associated protein-1 (NAC1), inhibits NAC1 homodimerization, leading to proteasomal NAC1 degradation. |
| PC-23325 |
Stomidazolone
Stomatal differentiation inhibitor
|
Stomidazolone is a doubly-sulfonylated imidazolone that inhibits stomatal differentiation, tightly binds to C-terminal ACT-Like (ACTL) domain of MUTE (Kd=8.9 uM) and perturbs the SCRM-MUTE heterodimerization. |
| PC-23304 |
PGMI-004A
PGAM1 inhibitor
|
PGMI-004A is a specific small molecule inhibitor of glycolytic enzyme phosphoglycerate mutase 1 (PGAM1) with IC50 of 13.1 uM, Ki of 3.91 uM. |
| PC-23289 |
C071-0684
CHD1L inhibitor
|
C071-0684 is a potent small molecule inhibitor of CHD1L targeting ATP catalytic activity of chromodomain helicase CHD1L (IC50=17.36 uM, KD=0.5 uM), shows IC50 of 13.0 uM against human HCT116 colorectal cancer cells. |
| PC-23260 |
Migalastat hydrochloride
α-Gal A inhibitor
|
Migalastat hydrochloride (GR181413A) is a potent and competitive inhibitor of alpha-galactosidase A (α-Gal A) with IC50 of 0.04 uM (human α-Gal A). |
| PC-23229 |
SLCB050
DX2-p14/ARF inhibitor
|
SLCB050 is a specific small molecule inhibitor of AIMP2-DX2-p14/ARF Interaction, inhibits lung cancer progression. |
| PC-23228 |
AM-001
EPAC1 inhibitor
|
AM-001 is a potent, selective and allosteric inhibitor of exchange proteins directly activated by cAMP 1 (EPAC1), inhibits Sp-8-CPT-induced Epac1 (EC50=47.8 uM) but not Epac2 activity. |
| PC-23227 |
Tirasemtiv
Fast skeletal troponin activator
|
Tirasemtiv (CK-2017357) is the first activator of fast skeletal muscle troponin with AC40 of 0.1 uM in in myofibril ATPase activity assays, shows potential for the treatment of amyotrophic lateral sclerosis. |
| PC-23216 |
hPIF1 inhibitor 6
PIF1 inhibitor
|
hPIF1 inhibitor 6 is a specific small molecule inhibitor targeting the helicase activity of human PIF1 with IC50 of 36 uM for inhibition of FLhPIF1 helicase activity, 22-fold selective over hUPF1, inhibits hPIF1 DNA-binding and helicase activity in vitro. |
| PC-23069 |
QC-308
Heme oxygenase inhibitor
|
QC-308 is a potent heme oxygenase (HO) inhibitor witn IC50 of 0.27 uM and 0.46 uM for hHO-1 and hHO-2 respectively. |
| PC-23067 |
CDD-3290
PSA inhibitor
|
CDD-3290 (CDD3290) is a specific small molecule inhibitor of prostate-specific antigen (PSA; KLK3) with Ki of 216 nM. |
| PC-22980 |
Peptide SBT-20
ROS-lowering peptide
|
Peptide SBT-20 (SS-20) is a cell-permeable peptide targeting the inner mitochondrial membrane, reduces ROS, normalizes electron transport chain function and ATP generation. |
