| Cat. No. |
Product Name |
Information |
| PC-23787 |
PFKFB2 inhibitor B2
PFKFB2 inhibitor
|
PFKFB2 inhibitor B2 is a small molecule inhibitor of PFKFB2 (6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 2) with IC50 of 3.29 uM, inhibits PFKFB3 with IC50 of 11.89 uM. |
| PC-23758 |
MTDH-SND1 PPI inhibitor C19
MTDH-SND1 inhibitor
|
MTDH-SND1 PPI inhibitor C19 is a small-molecule inhibitor of MTDH-SND1 PPI with IC50 of 487 nM, directly binds to the SND1-purified protein, degrades SND1 and downregulates downstream at the protein level. |
| PC-23750 |
Dauricine
STK11 agonist
|
Dauricine, a bisbenzylisoquinoline alkaloid in Menispermum dauricum, has anti-inflammatory activity, Dauricine is a natural agonist of STK11 (Serine/threonine kinase 11). |
| PC-23732 |
Ln268
PGK1 inhibitor
|
Ln268 is a potent Lin28 inhibitor, inhibits Lin28:pre-let-7d complex formation in a dose-dependent manner, inhibits Lin28b at both mRNA and protein level, specifically inhibits various Lin28-positive cancer cells. |
| PC-23722 |
QP5020
QPCTL inhibitor
|
QP5020 is a potent inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with IC50 of 15 nM. |
| PC-23698 |
SEPT9 inhibitor 8b
SEPT9 inhibitor
|
SEPT9 inhibitor 8b is a small molecule inhibitor of Septin 9 (SEPT9) with IC50 of 95 uM in fluorescence polarization (FP) assays, and binding KD of 22 uM, disrupts the structure of SEPT9, microtubules, and actin filaments. |
| PC-23697 |
Neocarzilin A
VAT1 inhibitor
|
Neocarzilin A (NCA) is a potent inhibitor of cancer cell migration, irreversibly binds to and inhibits the synaptic vesicle membrane protein VAT-1. |
| PC-23649 |
Genipin
UCP2 inhibitor
|
Genipin is a specific small molecule inhibitor of uncoupling protein 2 (UCP2), inhibits UCP2-mediated mitochondrial proton leak. |
| PC-23604 |
CCG257081
MRTF/SRF inhibitor
|
CCG-257081 is a small molecule MRTF/SRF pathway inhibitor, shows direct binding to pirin with ITC KD value of 8.6 uM, inhibits melanoma metastasis and bleomycin-induced fibrosis. |
| PC-23580 |
Licochalcone C
α-glycosidase inhibitor
|
Licochalcone C is a selective inhibitor of α-glycosidase with IC50 of <100 nM, does not inhibit PTP1B, induces apoptosis via Bcl-2 family proteins in T24 cells. |
| PC-23578 |
Licochalcone A
UGT inhibitor
|
Licochalcone A is a broad-spectrum inhibitor of UDP-glucuronosyltransferase (UGT) with IC50/Ki values of <5 uM for UGT1A1、1A3、1A4、1A6、1A7、1A9 and 2B7, shows anti-cancer effects, |
| PC-23556 |
Purpurin
GDH1 inhibitor
|
Purpurin is a potent, specific inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1) with Ki of 1.9 uM, inhibits cancer cell proliferation and tumor growth. |
