| Cat. No. |
Product Name |
Information |
| PC-23394 |
OGT 2115
Heparanase inhibitor
|
OGT 2115 is a potent, specific, cell-permeable and orally active heparanase inhibitor with IC50 of 0.4 uM, inhibits the expression and activity of heparanase. |
| PC-23379 |
BIM-46174
Heterotrimeric Gα/Gβγ inhibitor
|
BIM-46174 is a selective inhibitor of heterotrimeric G-protein complex Gα/Gβγ subunits, abrogates cancer cell invasion controlled by several GPCR agonists. |
| PC-23377 |
GQ127
Gαq/11 inhibitor
|
GQ127 is a potent, selective Gαq/11 signaling pathway inhibitor with IC50 of 22.4 uM. GQ127 shows good efficacy and safety in inositol monophosphate (IP1) assay by directly inhibiting Gαq/11 proteins. |
| PC-23352 |
MASTL-IN-1
MASTL inhibitor
|
MASTL-IN-1 is a potent, selective inhibitor of microtubule-associated serine/threonine kinase-like (MASTL, Greatwall) with Ki of 4.4 nM, cellular pENSA IC50 of 23 nM. |
| PC-23351 |
MASTL inhibitor 16
MASTL inhibitor
|
MASTL inhibitor 16 is a potent, highly selective inhibitor of microtubule-associated serine/threonine kinase-like (MASTL, Greatwall) with Ki of 0.12 nM, cellular pENSA IC50 of 2.8 nM in MDA-MB-231 cells. |
| PC-23350 |
MASTL inhibitor 15
MASTL inhibitor
|
MASTL inhibitor 15 is a potent, highly selective inhibitor of microtubule-associated serine/threonine kinase-like (MASTL, Greatwall) with Ki of <0.03 nM, cellular pENSA IC50 of 1.1 nM in MDA-MB-231 cells. |
| PC-23326 |
HPA-12
CERT inhibitor
|
HPA-12 is a small molecule inhibitor of ceramide trafficking/ceramide transporter (CERT), inhibits sphingomyelin biosynthesis. |
| PC-23324 |
SIM1
Stomatal opening inhibitor
|
SIM1 is a small molecule inhibitor of stomatal opening, inhibits the light induced stomatal opening of Arabidopsis with IC50 of 44.9 uM, affects stomatal aperture. |
| PC-23308 |
AK-778-XXMU
ID2 inhibitor
|
AK-778-XXMU is a small molecule inhibitor of protein ID2 (inhibitor of DNA binding 2) with SPR KD value of 129 nM. |
| PC-23287 |
HKi6
HEG1-KRIT1 inhibitor
|
HKi6 is a specific small-molecule HEG1-KRIT1 inhibitor (IC50=1.5 uM) by competing orthosterically with HEG1 for binding to the KRIT1 FERM domain, elevates KLF4 and KLF2 gene expression and increases Akt phosphorylation. |
| PC-23282 |
Malabaricone C
Sphingomyelin synthase inhibitor
|
Malabaricone C is a natural sphingomyelin synthase (SMS) inhibitor with IC50 values of 3 uM and 1.5 μM for SMS1 and SMS2, respectively. |
| PC-23220 |
VPS18 inhibitor RDN
VPS18 inhibitor
|
VPS18 inhibitor RDN is a specific lysosomotropic agent that targeting vacuole protein sorting 18 (VPS18), binds to the RING domain of VPS18, leading to disruption of the VPS-C core complex and lysosomal function. |
