| Cat. No. |
Product Name |
Information |
| PC-26215 |
Furin inhibitor 27
Furin inhibitor
|
Furin inhibitor 27 is a highly potent, small molecule inhibitor of proprotein convertase (PC) furin with Ki of 1.67 nM, also inhibits the structurally related PC7 with Ki of 7.27 nM. |
| PC-26214 |
MI-1851
Furin inhibitor
|
MI-1851 is a highly potent, peptidic mimetic inhibitor of furin with Ki of 10.1 pM, inhibits SARS-CoV-2 replication. |
| PC-26213 |
GLO1 inhibitor 3d
Glyoxalase I inhibitor
|
GLO1 inhibitor 3d is a potent glyoxalase I (GLO1) inhibitor with IC50 of 11 nM. |
| PC-26207 |
DB1033
Oct1/OCA-B inhibitor
|
DB1033 is a small molecule inhibitor of Oct1/OCA-B transcription complexes, inhibits cellular OCA-B activity with IC50 of 26.1 uM, disrupts the interaction between Oct1 and OCA-B. |
| PC-26206 |
164B8
Pin1 degrader
|
164B8 is a highly potent, covalent Pin1 inhibitor / degrader with IC50 of 4.65 nM, reacts with the Pin1 active-site residue Cys113, effectively induces Pin1 degradation both in cell and in vivo. |
| PC-26190 |
4-Methylumbelliferone
Hyaluronan biosynthesis inhibitor
|
4-Methylumbelliferone (4-MU) is a plant-derived coumarin and specific small molecule inhibitor of hyaluronan biosynthesis hyaluronan-mediated motility receptor (HMMR), shows antitumoral and antimetastatic effects. |
| PC-26189 |
Gαi2 inhibitor GT-14
Gαi2 inhibitor
|
GT-14 is a first-generation small molecule inhibitor of Gαi2 protein, inhibits cancer cell migration and prevents Gαi2 activation. |
| PC-26185 |
Biliverdin
114-25-0
|
Biliverdin is a prototypical tetrapyrrolic chromophore compound and HO-1 metabolic product, mediates the protective effects of HO-1 in many disease models including IRI and organ transplantation, exhibits anti-mutagenic, an antioxidant, anti-inflammatory, and immunosuppressant properties. |
| PC-26184 |
WGU55
TMPRSS6 inhibitor
|
WGU55 is a potent, selective peptidomimetic TMPRSS6 inhibitor with Ki of 12.15 nM and IC50 of 138 nM in TMPRSS6-transfected HEK293 cells, shows >200-fold selectivity over matriptase, Factor Xa and Thrombin. |
| PC-26151 |
PLAGL2 inhibitor Compound C8
PLAGL2 inhibitor
|
PLAGL2 inhibitor Compound C8 is a small-molecule inhibitor targeting PLAGL2 (Pleiomorphic adenoma-like protein 2) with SPR KD of 2.23 uM, inhibits PLAGL2 transcriptional activity and HCC cell viability (MHCC-97H, IC50=3.69 uM). |
| PC-26130 |
SR-1815
SynGAP rescuer
|
SR-1815 is a small molecule multi-kinase inhibitor, rescues SynGAP protein levels in heterozygous KO neurons and in the disease model with Syngap1 haploinsufficiency |
| PC-26113 |
JZ128
PKN3 inhibitor
|
JZ128 is a selective, covalent inhibitor of Protein Kinase N3 (PKN3) with IC50 of 120 nM, targets Cys840 in PKN3, has no activity against CDK7 or CDK12/13. |
