| Cat. No. |
Product Name |
Information |
| PC-20735 |
F83236
Cyclophilin inhibitor
|
F83236 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets. |
| PC-20717 |
RBP4 antagonist 59
RBP4 inhibitor
|
RBP4 antagonist 59 is a potent, selective and orally bioavailable retinol-binding protein 4 (RBP4) antagonist with HTRF IC50 of 16 nM. |
| PC-20703 |
IOI-42
hPEBP4 inhibitor
|
hPEBP4 inhibitor IOI-42 is a small molecule inhibitor of anti-apoptotic protein hPEBP4, potentiates TNF-α-mediated growth inhibition of MCF-7 breast cancer cells. |
| PC-20670 |
M3913
WFS1 inhibitor
|
M3913 is a potential, first-in-class WFS1 transmembrane glycoprotein-targeting unfolded protein response (UPR) inducer (ER stress modulator) with EC50 of 1.5 uM for CHOP induction in vitro. |
| PC-20613 |
Perforin inhibitor 3
Perforin inhibitor
|
Perforin inhibitor 3 is a small molecule Perforin inhibitor, inhibits perforin-induced lysis of Jurkat T-lymphoma cells with IC50 of 0.78 uM. |
| PC-20612 |
Perforin inhibitor 2
Perforin inhibitor
|
Perforin inhibitor 2 is a small molecule Perforin inhibitor, inhibits perforin-induced lysis of Jurkat T-lymphoma cells with IC50 of 1.19 uM. |
| PC-20611 |
Perforin inhibitor 1
Perforin inhibitor
|
Perforin inhibitor 1 is a small molecule Perforin inhibitor, inhibits perforin-induced lysis of Jurkat T-lymphoma cells with IC50 of 2.3 uM. |
| PC-20610 |
Perforin inhibitor 5
Perforin inhibitor
|
Perforin inhibitor 5 is a small molecule Perforin inhibitor, inhibits perforin-induced lysis of Jurkat T-lymphoma cells with IC50 of 1.17 uM. |
| PC-20595 |
NS5806
cTnC activator
|
NS5806 is a small molecule cardiac troponin (cTnC) activator, binds to Ca2+-saturated cChimera with Kd of 7.6 uM, stabilizes active troponin, significantly increases the ATPase activity of cardiac myofibrils in a dose-dependent manner. |
| PC-20569 |
ERAD inhibitor CP26
Dislocation inhibitor
|
ERAD inhibitor CP26 (NSC26112) is a small molecule inhibitor of Hrd1 complex-mediated dislocation, inhibits NHK dislocation in HeLa cells with IC50 of 4.45 μM in the drGFP assays, shows broad-spectrum anti-flavivirus activity. |
| PC-49726 |
Seletracetam
SV2A ligand
|
Seletracetam (ucb 44212) is a high affinity for the synaptic vesicle protein 2A (SV2A) than levetiracetam with 10-fold, exhibits anticonvulsant properties in animal models of epilepsy. |
| PC-49471 |
MO-I-1100
ASPH inhibitor
|
MO-I-1100 is a small molecule inhibitor of aspartyl-(asparaginyl)-β-hydroxylase (ASPH), inhibits the β-hydroxylase activity of ASPH about 80%, inhibits Notch signaling in HCC cancer cells. |
