| Cat. No. |
Product Name |
Information |
| PC-26390 |
ONO-6428513
GCLC inhibitor
|
ONO-6428513 (GCLCi0) is a potent, selective glutamylcysteine ligase catalytic subunit (GCLC) inhibitor, shows potent anti-tumor effects in SMARCB1-deficient cancer cells. |
| PC-26389 |
CZ-48
SARM1 activator
|
CZ-48 (Sulfo-ara-F-NMN) is a mimetic of nicotinamide mononucleotide (NMN) and selective cell-permeant activator of SARM1, activate SARM1 to produce cADPR from NAD, does not inhibit CD38. |
| PC-26378 |
Z-5891
COPS3 inhibitor
|
Z-5891 is a highly selective COPS3 inhibitor, exhibits concentration-dependent proliferation-inhibitory activity against 143B cells with IC50 of 3.28 uM. |
| PC-26374 |
Aflatoxin B1
1162-65-8
|
Aflatoxin B1 (AFB1) is a Group 1A carcinogen and a secondary metabolite produced by Aspergillus flavus and A. parasiticus, can induces mutations by causing a G to T transversion at the third nucleotide of codon 249 in the tumor suppressor gene p53. |
| PC-26361 |
Ubiquinol
Antioxidant
|
Ubiquinol (Coenzyme Q10, CoQ10) is a compound thatmitochondria need to make energy, is also a strong antioxidant that protects cell membranes and keeps them stable, while helping prevent LDL cholesterol from oxidizing. |
| PC-26346 |
Obuprazine
2640663-79-0
|
Obuprazine is a small molecule G protein-coupled receptor modulator in the treatment or prevention of central nervous system diseases and/or mental diseases. |
| PC-26340 |
Mezodriton
Mitochondrial uncoupler
|
Mezodriton is a small molecule mitochondrial oxidative phosphorylation uncoupler. |
| PC-26336 |
Lomasemtiv
Troponin activator
|
Lomasemtiv is a small molecule troponin activator. |
| PC-26334 |
Linepemat
1211876-03-7
|
Linepemat is a small molecule mudulator of cortical catecholaminergic neurotransmission. |
| PC-26323 |
Dinifedriton
Mitochondrial uncoupler
|
Dinifedriton is a small molecule mitochondrial uncoupler for regulating mitochondria activity and reducing adiposity in the treatment of diseases. |
| PC-26308 |
GIT1/β-Pix inhibitor 14-5-18
GIT1/β-Pix inhibitor
|
GIT1/β-Pix inhibitor 14-5-18 is a small-molecule inhibitor to interrupt the protein–protein interaction (PPI) of GIT1/β-Pix complex with Ki of 1.8 uM in FP assays, directly binds to GIT1 with BLI KD of 7.7 uM, inhibits gastric cancer metastasis. |
| PC-26306 |
GIT1 inhibitor Compound 3
GIT1 inhibitor
|
GIT1 inhibitor Compound 3 (GIT1-IN-C3) is a selective small molecule inhibitor of ARF GTPase protein 1 (GIT1) with MST KD of 6.2 uM, effectively disrupts GIT1 from interacting with MAT2B and RAF/MEK/ERK to halt cancer cell growth in vitro and in vivo. |
