| Cat. No. |
Product Name |
Information |
| PC-25214 |
I942
EPAC1 agonist
|
I942 is a specific, small molecule partial agonist of cyclic AMP sensor EPAC1 with AC50 of 50 uM, shows no effect on EPAC2. |
| PC-25207 |
YB-B1
YBX1 inhibitor
|
YB-B1 is a small molecule Y-box-binding protein 1 (YBX1) inhibitor, directly binds to YBX1 protein with SPR KD value of 5.67 uM. |
| PC-25203 |
Pin1 inhibitor PiB
Pin1 inhibitor
|
Pin1 inhibitor PiB is a specific small molecule inhibitor of parvulin family peptidyl prolyl isomerase (PPIase) Pin1 with IC50 of 1.5 uM, inhibits Par14 as potently as Pin1 with IC50 of 1.0 uM. |
| PC-25177 |
Compound 22978-61-6
Tryptase β inhibitor
|
Compound 22978-61-6 (MFCD00173785) is a potent, selective inhibitor of tryptase β, exhibits potent, dose-dependent inhibition of human pancreatic stellate cells (HPSCs) proliferation at 1 uM. |
| PC-25176 |
BMS-354326
Tryptase inhibitor
|
BMS-354326 is a highly potent, selective tryptase inhibitor with IC50 of 1.8 nM, shows excellent selectivity against trypsin and most other related serine proteases. |
| PC-25175 |
BMS-363131
Tryptase inhibitor
|
BMS-363131 is a potent, selective inhibitor of tryptase with IC50 of <1.7 nM, having excellent selectivity versus other serine proteases including trypsin. |
| PC-25174 |
BMS-262084
Tryptase inhibitor, FXIa inhibitor
|
BMS-262084 is a potent and highly selective inhibitor of human tryptase with IC50 of 4 nM, >100-fold selective over Plasmin, Thrombin, uPA and tPA, also is an irreversible inhibitor of factor Xia with IC50 of 2.8 nM, shows antithrombotic effects. |
| PC-25173 |
Pyrabactin
ABA receptor agonist
|
Pyrabactin is a specific, synthetic abscisic acid (ABA) agonist that selectively inhibits seed germination, promotes interactions between HAB1 and PYR1, PYL1 or PYL3. |
| PC-25172 |
AMF4
ABA receptor agonist
|
AMF4 is synthetic ABA-mimicking ligand and potent agonist of PYL proteins PYR1, PYL1, PYL2, and PYL7 with binding EC50 of 47-120 nM, induces genes involved in abiotic-stress resistance, regulates ABA-responsive genes in Arabidopsis plants. |
| PC-25171 |
Cyanabactin
ABA receptor agonist
|
Cyanabactin is a potent and selective plant hormone abscisic acid (ABA) receptor agonist that preferentially activates Pyrabactin Resistance 1 (PYR1) with low nanomolar potency, exhihibits a wide spectrum of ABA-like activities. |
| PC-25170 |
ABA receptor agonist iCB
ABA receptor agonist
|
ABA receptor agonist iCB is a novel synthetic abscisic acid (ABA) receptor agonist with broad-spectrum activation across the three receptor subtypes, has IC50 of 0.16 uM in seedling establishment inhibition assay. |
| PC-25150 |
MIF inhibitor 4-IPP
MIF inhibitor
|
MIF inhibitor 4-IPP is a specific, irreversible, suicide substrate inhibitor of macrophage migration inhibitory factor (MIF). |
