| Cat. No. |
Product Name |
Information |
| PC-26181 |
CAPib-13
CAP-1 inhibitor
|
CAPib-13 is a small-molecule inhibitor of CAP-1 (cyclase-associated protein-1) with SPR KD of 2.57 uM, significantly suppresses colorectal cancer metastasis. |
| PC-26151 |
PLAGL2 inhibitor Compound C8
PLAGL2 inhibitor
|
PLAGL2 inhibitor Compound C8 is a small-molecule inhibitor targeting PLAGL2 (Pleiomorphic adenoma-like protein 2) with SPR KD of 2.23 uM, inhibits PLAGL2 transcriptional activity and HCC cell viability (MHCC-97H, IC50=3.69 uM). |
| PC-26148 |
NFAT Inhibitor VIVIT peptide
NFAT inhibitor
|
NFAT Inhibitor VIVIT peptide is a peptide inhibitor of nuclear factor of activated Tcells (NFAT), selectively inhibits calcineurin-mediated dephosphorylation of NFAT. |
| PC-26147 |
A-285222
NFAT inhibitor
|
A-285222 (A-285) is a bis-trifluoromethyl-pyrazole (BTP) and selective nuclear factor of activated T cells (NFAT) inhibitor, inhibits PBMC proliferation stimulated by concanavalin A with IC50 of 146 nM, inhibits IL-2 synthesis in human blood with IC50 of 182 nM. |
| PC-26146 |
INCA-6
NFAT inhibitor
|
INCA-6 (Inhibitor of NFAT-calcineurin association 6) is a specific, cell-permeable nuclear factor of activated T cells (NFAT) inhibitor, binds to calcineurin with high affinity (KD=0.8 uM) and specifically disrupts its interaction with NFAT. |
| PC-26130 |
SR-1815
SynGAP rescuer
|
SR-1815 is a small molecule multi-kinase inhibitor, rescues SynGAP protein levels in heterozygous KO neurons and in the disease model with Syngap1 haploinsufficiency |
| PC-26113 |
JZ128
PKN3 inhibitor
|
JZ128 is a selective, covalent inhibitor of Protein Kinase N3 (PKN3) with IC50 of 120 nM, targets Cys840 in PKN3, has no activity against CDK7 or CDK12/13. |
| PC-26112 |
GSK902056A
PKN3 inhibitor
|
GSK902056A is a highly potent inhibitor of serine/threonine kinase PKN3 with Kdapp of 1 nM, potently engaged PKN3 in cells with IC50 of 79 nM. |
| PC-26108 |
Py-Pip
Neurolysin activator
|
Py-Pip is a nonpeptide small molecule activator of Neurolysin (Nln), enhances the activity of peptidase neurolysin. |
| PC-26095 |
Profilin1 inhibitor UP-6
Profilin1 inhibitor
|
Profilin1 inhibitor UP-6 is a specific small molecule inhibitor of Actin-binding protein profilin1 (Pfn1), inhibits Pfn1-actin interaction and tumor angiogenesis. |
| PC-26091 |
Etoxazole
Acaricide
|
Etoxazole (YI-5301) is a highly effective acaricide that affects the nymphs, eggs, and larvae of spider mites by inhibiting chitin biosynthesis. |
| PC-26087 |
MKV3
Cu+-ATPases inhibitor
|
MKV3 is a specific, first-in-class, broad spectrum inhibitor of Cu-transporting P-type ATPases targeting P1B-type copper ATPases, binds within the Cu+ entry pocket, thereby blocking Cu+ delivery to the intramembranous transport site, dependently decreases Cu+-stimulated ATPase activity with IC50 of 130 nM for Escherichia coli Cu+-ATPase CopA (EcCopA). |
