| Cat. No. |
Product Name |
Information |
| PC-23178 |
SCR-7952
MAT2A inhibitor
|
SCR-7952 is a potent, highly selective methionine adenosyltransferase 2A (MAT2A) inhibitor with IC50 of 18.7 nM, Ki of 14.49 nM, shows MTAP-null selective antiproliferative activity. |
| PC-23122 |
FUT8 Inhibitor 40
FUT8 inhibitor
|
FUT8 Inhibitor 40 (FUT8-IN-2) is a selective, cell-active inhibitor of α-1,6-fucosyltransferase (FUT8), inhibits FUT8 without inhibiting other FUTs. |
| PC-23069 |
QC-308
Heme oxygenase inhibitor
|
QC-308 is a potent heme oxygenase (HO) inhibitor witn IC50 of 0.27 uM and 0.46 uM for hHO-1 and hHO-2 respectively. |
| PC-23067 |
CDD-3290
PSA inhibitor
|
CDD-3290 (CDD3290) is a specific small molecule inhibitor of prostate-specific antigen (PSA; KLK3) with Ki of 216 nM. |
| PC-23025 |
GSDMD agonist DMB
Gasdermin D agonist
|
GSDMD agonist DMB is a direct and selective gasdermin D (GSDMD) agonist, activates GSDMD pore formation to trigger liposome leakage with EC50 of 0.7 uM, activates GSDMD pore formation and pyroptosis without cleaving GSDMD. |
| PC-23021 |
SRSF10 inhibitor 1C8
SRSF10 inhibitor
|
SRSF10 inhibitor 1C8 is a specific small molecule inhibitor of SRSF10, alters splicing regulation mediated by SRSF10, shows strong anti-HIV-1 potency against a variety of clinical strains in vitro. |
| PC-22980 |
Peptide SBT-20
ROS-lowering peptide
|
Peptide SBT-20 (SS-20) is a cell-permeable peptide targeting the inner mitochondrial membrane, reduces ROS, normalizes electron transport chain function and ATP generation. |
| PC-22860 |
GZ667161
Glucosylceramide synthase inhibitor
|
GZ667161 (Genz-667161) is potent, orally available and CNS-penetrant inhibitor of Glucosylceramide synthase (GCS), alleviates aberrations in synucleinopathy models. |
| PC-22844 |
LXG6403
LOX inhibitor
|
LXG6403 is a highly potent, irreversible lysyl oxidase (LOX) inhibitor, inhibits cellular LOX activity efficiently in MDA-MB-231 cells with IC50 of 1.3 uM, >3-fold selective over LOXL2 and no activity against LOXL1. |
| PC-22799 |
BCATc inhibitor 2
BCAT1 inhibitor
|
BCATc inhibitor 2 (Bi2) is a specific inhibitor of cytosolic branched-chain aminotransferase (BCATc, BCAT1) with IC50 of 0.2/ 0.8 uM for rat/human BCATc respectively, weakly inhibits rat mitochondrial isoenzyme rBCATm. |
| PC-22793 |
BIIB-TTBKi
TTBK1 inhibitor
|
BIIB-TTBK1i is a potent selective inhibitor of CNS-specific tau kinase Tau Tubulin Kinase 1 (TTBK1) with IC50 of 9.5 nM in recombinant kinase assay, inhibits tau phosphorylation at S422 (pS422) with IC50 of 9.75 nM in cell-based assays. |
| PC-22792 |
TTBK1 inhibitor 31
TTBK inhibitor
|
TTBK1 inhibitor 31 (TTBK1-IN-1) is a potent, selective and CNS-penetrant Tau Tubulin Kinase 1 (TTBK1) inhibitor with IC50 of 2.7 nM, inhibits tau phosphorylation at the disease-relevant Ser 422 epitope. |
