| Cat. No. |
Product Name |
Information |
| PC-24293 |
HypoxyStat
Hypoxia inducer
|
HypoxyStat is a small molecule that increase oxygen-hemoglobin binding affinity cause tissue hypoxia, binds hemoglobin, induces systemic hypoxia in mice breathing normoxic (21% O2) air. |
| PC-24222 |
I3MT-3
3MST inhibitor
|
I3MT-3 (HMPSNE, 3MST inhibitor 3) is a potent, selective, cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) with IC50 of 2.7 uM. |
| PC-24123 |
Dencatistat
CTPS1 inhibitor
|
Dencatistat (STP938) is a potent, orally bioavailable, selective inhibitor of cytidine triphosphate synthase 1 (CTPS1) with IC50 of <100 nM, specifically blocks cell proliferation of the hematological cancers. |
| PC-24108 |
LIBX-A401
ACSL4 inhibitor
|
LIBX-A401 is a potent, selective inhibitor of Acyl-coenzyme A synthetase long-chain family member 4 (ACSL4) with IC50 of 0.38 uM, MST KD of 0.72 uM, with high selectivity over ACSL3 (IC50>50 uM), protects cells from ferroptosis. |
| PC-24039 |
RUN-47
NRF1 activator
|
RUN-47 is a small-molecule activator of NRF1 with EC50 of 6.43 uM in 3xPSMA4-ARE-LUC reporter assays, specifically activates NRF1 pathway. |
| PC-23917 |
JH-ENT-01
ENT1 inhibitor
|
JH-ENT-01 is a potent, specific inhibitor of the equilibrative nucleoside transporter subtype 1 (ENT1) with Ki of 92.7 nM, shows good selectivity for hENT1 over hENT2. |
| PC-23912 |
TN2008
SRSF1 inhibitor
|
TN2008 is an effective serine arginine-rich splicing factor 1 (SRSF1) inhibitor with IC50 of 144 uM, exhibits high affinity for recombinant SRSF1 with Kd of 5.13 uM in SPR assays. |
| PC-23857 |
VK-2019
EBNA1 inhibitor
|
VK-2019 is a selective small molecule inhibitor of Epstein-Barr virus Nuclear Antigen 1 (EBNA1), reduces EBV genome copy number and viral gene expression in EBV-positive nasopharyngeal carcinoma. |
| PC-23850 |
ALT-007
Serine palmitoyltransferase inhibitor
|
ALT-007 is a potent, selective and orally bioavailable inhibitor of serine palmitoyltransferase (SPT) with enzyme IC50 of 0.54 nM. |
| PC-23833 |
EOS301984
ENT1 inhibitor
|
EOS301984 (EOS-984) is a potent, selective equilibrative nucleoside transporter 1 (ENT1) antagonist with IC50 of 339.6 nM (human ENT1), 150-fold selectivity for ENT1 versus ENT2. |
| PC-23824 |
Paquinimod
S100A9 inhibitor
|
Paquinimod (ABR-215757) is a specific inhibitor of S100A9, inhibits S100A8/S100A9 binding to RAGE, reduces diabetes-induced thrombocytosis. |
| PC-23783 |
BL001
LRH-1 agonist
|
BL001 is a specific small molecule agonist of liver receptor homologue-1 (LRH-1) with EC50 of 0.1 uM, specifically binds to and activates LRH-1. |
