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YKJ-86

Chemical Structure : YKJ-86

CAS No.:

YKJ-86 (YKJ86)

货号: PC-27983Not For Human Use, Lab Use Only.

YKJ-86 is a potent, pan-inhibitor of cholesterol transfer proteins Aster-A, -B, and -C, effectively blocks Aster-mediated cholesterol transport in a concentration-dependent manner and completely inhibits cholesterol transport at 10 uM in CHO-K1 cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

YKJ-86 is a potent, pan-inhibitor of cholesterol transfer proteins Aster-A, -B, and -C, effectively blocks Aster-mediated cholesterol transport in a concentration-dependent manner and completely inhibits cholesterol transport at 10 uM in CHO-K1 cells.

物理化学性质&存储条件

分子量 294.35
分子式 C18H18N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(6-(6-methoxypyridin-3-yl)quinolin-2-yl)propan-2-ol

参考文献

1. Hyunsoo Kim, et al. Proc Natl Acad Sci U S A. 2026 Sep 8;123(36):e2617638123.

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