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Rusfertide

Chemical Structure : Rusfertide

CAS No.: 1628323-80-7

Rusfertide (PTG-300, PTG300)

货号: PC-28065Not For Human Use, Lab Use Only.

Rusfertide (PTG-300) is a peptidic mimetic of hepcidin that binds to ferroportin and decreases iron delivery to bone marrow, reducing the production of red blood cells, shows potential for polycythemia vera and hemochromatosis.

规格 价格 库存 数量
5 mg ¥1980 In stock
10 mg ¥3280 In stock
25 mg ¥5280 In stock
50 mg Get quote
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Rusfertide (PTG-300) is a peptidic mimetic of hepcidin that binds to ferroportin and decreases iron delivery to bone marrow, reducing the production of red blood cells, shows potential for polycythemia vera and hemochromatosis.

物理化学性质&存储条件

分子量 2441.95
分子式 C114H181N27O28S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Lysinamide, N-(3-methyl-1-oxobutyl)-L-α-aspartyl-L-threonyl-L-histidyl-L-phenylalanyl-L-prolyl-L-cysteinyl-L-isoleucyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-phenylalanyl-L-α-glutamyl-L-prolyl-L-arginyl-L-seryl-L-lysylglycyl-L-cysteinyl-, cyclic (6→16)-disulfide

参考文献

1. Kremyanskaya M, et al. N Engl J Med. 2024 Feb 22;390(8):723-735.

2. Modi NB, et al. Eur J Haematol. 2024 Sep;113(3):340-350.

3. Chew LP, et al. Leuk Res. 2025 Dec;159:108132.

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