Chemical Structure : Rusfertide
CAS No.: 1628323-80-7
货号: PC-28065Not For Human Use, Lab Use Only.
Rusfertide (PTG-300) is a peptidic mimetic of hepcidin that binds to ferroportin and decreases iron delivery to bone marrow, reducing the production of red blood cells, shows potential for polycythemia vera and hemochromatosis.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | ¥1980 | In stock | |
| 10 mg | ¥3280 | In stock | |
| 25 mg | ¥5280 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Rusfertide (PTG-300) is a peptidic mimetic of hepcidin that binds to ferroportin and decreases iron delivery to bone marrow, reducing the production of red blood cells, shows potential for polycythemia vera and hemochromatosis.
| 分子量 | 2441.95 | |
| 分子式 | C114H181N27O28S2 | |
| 外观性状 | Solid | |
| 储存条件 |
|
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
L-Lysinamide, N-(3-methyl-1-oxobutyl)-L-α-aspartyl-L-threonyl-L-histidyl-L-phenylalanyl-L-prolyl-L-cysteinyl-L-isoleucyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-phenylalanyl-L-α-glutamyl-L-prolyl-L-arginyl-L-seryl-L-lysylglycyl-L-cysteinyl-, cyclic (6→16)-disulfide |
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1. Kremyanskaya M, et al. N Engl J Med. 2024 Feb 22;390(8):723-735.
2. Modi NB, et al. Eur J Haematol. 2024 Sep;113(3):340-350.
3. Chew LP, et al. Leuk Res. 2025 Dec;159:108132.
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