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EC134

Chemical Structure : EC134

CAS No.:

EC134 (EC-134)

货号: PC-28035Not For Human Use, Lab Use Only.

EC134 is a potent, cell-active small-molecule inhibitor of CBX7 with IC50 of 34 uM in FP assays, inhibits viability of OCI-AML3 with IC50 of 22 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

EC134 is a potent, cell-active small-molecule inhibitor of CBX7 with IC50 of 34 uM in FP assays, inhibits viability of OCI-AML3 with IC50 of 22 uM.

物理化学性质&存储条件

分子量 430.55
分子式 C26H30N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(4-(5-(2,6-dimethylphenyl)-6-methylpyridin-2-yl)piperazine-1-carbonyl)-1-ethylpyridin-2(1H)-one

参考文献

1. Chelsea R Wilson, et al. RSC Med Chem. 2026 Aug 7. doi: 10.1039/d6md00215c.

2. Anne P de Groot, et al. Blood Neoplasia. 2024 Oct 24;1(4):100052.

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