| Cat. No. |
Product Name |
Information |
| PC-21575 |
BiTud
TDRD3 inhibitor
|
BiTud is a bivalent inhibitor against TDRD3 with binding Kd of 6 uM for tandem Tudor chimera, blocks the recruitment of TDRD3 by the two methylated arginines of G3BP1, suppress the phase separation of methylated G3BP1, TDRD3, and RNAs, and in turn inhibits the stress granule growth in cells. |
| PC-21523 |
DS68591889
PTDSS1 inhibitor
|
DS68591889 (PTDSS1i) is a potent, selective phosphatidylserine synthase 1 (PTDSS1) inhibitor, highly sellective over PTDSS2, induces phospholipid imbalance in a wide range of cancer cells. |
| PC-21516 |
HJ445A
Myoferlin inhibitor
|
HJ445A is a highly potent, selective myoferlin (MYOF) inhibitor, binds to MYOF-C2D domain with KD value of 0.17 uM. |
| PC-21430 |
WDR91-IN-1
WDR91 binder
|
WDR91-IN-1 (WDR91 binder 1) is a small molecule ligand of WD40 repeat-containing protein 91 (WDR91) with SPR KD value of 6 uM. |
| PC-21417 |
HQY436
CPSF3 inhibitor
|
HQY436 is a specific, orally bioavailable inhibitor of pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3) with binding IC50 of 0.15 uM, exhibits potent antitumor activity. |
| PC-21416 |
HQY426
CPSF3 inhibitor
|
HQY426 is a specific, orally bioavailable inhibitor of pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3) with binding IC50 of 0.32 uM, exhibits potent antitumor activity. |
| PC-21410 |
LY3522348
Ketohexokinase (KHK) inhibitor
|
LY3522348 is a potent, highly selective, oral dual inhibitor of human ketohexokinase isoforms C and A (hKHK-C, hKHK-A) with IC50 of 20 nM and 24 nM, respectively. |
| PC-21391 |
IMB0901
Myostatin inhibitor
|
IMB0901 is a small molecule myostatin (MSTN) inhibitor that inhibits the MSTN promoter activity, the MSTN signaling pathway, and the MSTN positive feedback regulation. |
| PC-21385 |
PXS-5505 dihydrochloride monohydrate
pan-LOX inhibitor
|
PXS-5505 dihydrochloride monohydrate is an orally available, small-molecule, irreversible inhibitor of all lysyl oxidases (pan-LOX) family members, with potential antifibrotic activity. |
| PC-21383 |
IBS007125
c-Maf inhibitor
|
IBS007125 is a small molecule inhibitor of c-Maf, inhibits multiple myeloma proliferation by targeting cMaf transcriptional activity. |
| PC-21350 |
IP-DNQ
NQO1 inhibitor
|
IP-DNQ (Isopentyl-deoxynboquinone) is a small molecule that selectively kills pancreatic ductal adenocarcinoma cells in an NQO1-dependent manner. |
| PC-21347 |
Karyostatin 1A
Importin β inhibitor
|
Karyostatin 1A is a small molecule inhibitor of importin beta with binding affinity (Kd=0.3 uM), selectively inhibits the importin α/β pathway. |
