(+)-dMGer ((R)-dMGer) | KAI2 agonist | Probechem Biochemicals

Chemical Structure : (R)-dMGer

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(R)-dMGer ((+)-dMGer)

货号: PC-24061Not For Human Use, Lab Use Only.

(+)-dMGer ((R)-dMGer) is a potent agonist of Karrikin Insensitive 2 (KAI2), inhibits KAI2 hydrolytic activity with IC50 of 0.16 uM.

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生物&药学活性

(+)-dMGer ((R)-dMGer) is a potent agonist of Karrikin Insensitive 2 (KAI2), inhibits KAI2 hydrolytic activity with IC50 of 0.16 uM.
(+)-dMGer induced the interaction of KAI2 with SMAX1 at a 1 µM concentration.
(+)-dMGer dramatically decreases the Tm value of KAI2 from 51.6 to 33.4 °C with increasing ligand concentrations.
(+)-dMGer (0.03-0.3 uM) strongly inhibited hypocotyl elongation in Arabidopsis hypocotyl elongation assay
(+)-dMGer promoted the germination of thermoinhibited seeds from a concentration of 0.01 µM.

物理化学性质&存储条件

分子量	297.27
分子式	C16H11NO5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-5-((3-nitro-[1,1'-biphenyl]-4-yl)oxy)furan-2(5H)-one

参考文献

1. Kushihara R, et al. Proc Natl Acad Sci U S A. 2025 Feb 25;122(8):e2414779122.

(R)-dMGer ((+)-dMGer)

生物&药学活性

物理化学性质&存储条件

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(R)-dMGer ((+)-dMGer)

生物&药学活性

物理化学性质&存储条件

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