| Cat. No. |
Product Name |
Information |
| PC-22534 |
TSLP inhibitor BP79
TSLP inhibitor
|
TSLP inhibitor BP79 is a specific small molecule inhibitor of thymic stromal lymphopoietin (TSLP), disrupts TSLP-TSLP receptor interaction and effectively abrogates TSLP-triggered cytokines at low micromolar concentrations. |
| PC-22494 |
CCG-1423
MKL1/SRF inhibitor
|
CCG-1423 (CCG1423) is a small-molecule inhibitor of RhoA transcriptional signaling and serum response factor (SRF), blocks transcription activated by MKL1, disrupts transcriptional responses of the Rho pathway in cancer. |
| PC-22481 |
Forchlorfenuron
Septin inhibitor, HER2 inhibitor
|
Forchlorfenuron (CPPU, 4PU30) is a substituted phenylurea compound and synthetic plant cytokinin for inducing somatic embryogenesis in peanut (Arachis hypogaea L.), inhibits septin and protrusion formation, inhibits proliferation, migration, and invasion in human cancer cell lines, affects HIF-1α and HER2. |
| PC-22469 |
BI-43
Glutaminyl cyclase inhibitor
|
BI-43 is a potent, selective glutaminyl cyclase inhibitor with IC50 of 12 nM and 40 nM for both sQC and gQC, respectively. |
| PC-22448 |
CMFT
MIF inhibitor
|
CMFT is a a small molecule inhibitor of the functional interaction between the transcription factor ICBP90 (a.k.a. UHRF1) and the MIF-794 CATT5-8 promoter microsatellite, inhibits MIF mRNA expression in a -794 CATT5-8 length-dependent manner with an IC50 of 470 nM. |
| PC-22442 |
UCM-13369
NPM1 inhibitor
|
UCM-13369 is a small molecule inhibitor of nucleophosmin 1 (NPM1), inhibits NPM1 expression, downregulates the pathway associated with mutant NPM1 C+, inhibits tumorsphere growth of CSCs. |
| PC-22397 |
UNC9750
IPMK inhibitor
|
UNC9750 is a potent selective inhibitor of inositol phosphate multikinase (IPMK) with IC50 of 31.6 nM, inhibits human glioblastoma cell growth and selectively decreases cellular InsP5 abundance. |
| PC-22384 |
ML281
STK33 inhibitor
|
ML281 is a potent, selective inhibitor of serine/threonine kinase STK33 with IC50 of 14 nM, >500-fold selective over PKA and AurB. |
| PC-22383 |
CDD-2807
STK33 inhibitor
|
CDD-2807 is a highly potent, selective inhibitor of serine/threonine kinase 33 (STK33) with biochemically Kd of 0.02 nM, IC50 of 9.2 nM in NanoBRET assays, induces contraceptive effect. |
| PC-22367 |
SHP1705
CRY2 activator
|
SHP1705 is a small molecule cryptochrome 2 (CRY2) activator and stabilizer, represses the expression of DBP, CRY1, and PER1, reduces glucose intolerance in obese, insulin-resistant mice. |
| PC-22338 |
STL427944
FOXM1 inhibitor
|
STL427944 is a small molecule inhibitor of forkhead box protein M1 (FOXM1), selectively suppresses FOXM1 by inducing the relocalization of nuclear FOXM1 protein to the cytoplasm and promoting its subsequent degradation by autophagosomes. |
| PC-22337 |
STL001
FOXM1 inhibitor
|
STL001 is a small molecule inhibitor of forkhead box protein M1 (FOXM1), suppresses FOXM1 protein levels in a variety of solid tumor-derived cancer cell lines. |
