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首页-小分子抑制剂&激动剂-Others-Other Targets-SHP1705
SHP1705

Chemical Structure : SHP1705

CAS No.: 1817737-04-4

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SHP1705 (Cryptochrome modulator 50)

货号: PC-22367Not For Human Use, Lab Use Only.

SHP1705 is a small molecule cryptochrome (CRY) modulator and stabilizer, represses the expression of DBP, CRY1, and PER1, reduces glucose intolerance in obese, insulin-resistant mice.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SHP1705 is a small molecule cryptochrome (CRY) modulator and stabilizer, represses the expression of DBP, CRY1, and PER1, reduces glucose intolerance in obese, insulin-resistant mice.

物理化学性质&存储条件

分子量 345.35
分子式 C18H17F2N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(3-(3,6-difluoro-9H-carbazol-9-yl)-2-hydroxypropyl)imidazolidin-2-one

参考文献

1. Paul S Humphries, et al. Bioorg Med Chem Lett. 2018 Feb 1;28(3):293-297.

2. Yuanzhong Pan, et al. bioRxiv [Preprint]. 2024 Apr 29:2024.04.26.590360.

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