| Cat. No. |
Product Name |
Information |
| PC-24837 |
NGI-189
Oligosaccharyltransferase inhibitor
|
NGI-189 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.09 uM. |
| PC-24833 |
Pinosylvin
CAS 22139-77-1
|
Pinosylvin is a naturally occurring molecule traditionally found in pinus trees with antibacterial, antifungal and anticancer activity, shows potent growth inhibitory activity against Candida albicans and Saccharomyces cerevisiae. |
| PC-24820 |
KS122-0485428
Lysyl hydroxylase 2 inhibitor
|
KS122-0485428 is a specific small molecule inhibitor of Lysyl hydroxylase 2 (LH2), significantly enhances LH2 function in telopeptidyl Lys hydroxylation, cross-linking, and mineralization. |
| PC-24811 |
NSD-1015
AADC inhibitor
|
NSD-1015 (3-Hydroxybenzylhydrazine) is a specific small molecule inhibitor of aromatic L-amino acid decarboxylase (AADC). |
| PC-24805 |
Benserazide hydrochloride
AADC inhibitor,
|
Benserazide hydrochloride is a selective, peripherally acting aromatic L-amino acid decarboxylase (AADC) inhibitor, also is a potent inhibitor of bacterial T4P assembly ATPase PilB with IC50 of 3.68 uM. |
| PC-24792 |
VG-3927
TREM2 agonist
|
VG-3927 (I-192) is a highly potent, selective and brain penetrant triggering receptor expressed on myeloid cells 2 (TREM2) agonist. |
| PC-24791 |
TREM2 activator 4a
TREM2 agonist
|
TREM2 activator 4a is a specific small molecule activator of triggering receptor expressed on myeloid cells 2 (TREM2) with KD of 12.7 uM, 1.5-fold selectivity over TREM1, induces SYK phosphorylation and significantly enhances microglial phagocytic activity. |
| PC-24790 |
TREM2 activator 4i
TREM2 agonist
|
TREM2 activator 4i is a specific small molecule activator of triggering receptor expressed on myeloid cells 2 (TREM2) with KD of 19.0 uM in MST assays, 2-fold selectivity over TREM1, induces SYK phosphorylation and significantly enhances microglial phagocytic activity. |
| PC-24789 |
Mitochonic acid 5
ATP synthesis modulator
|
Mitochonic acid 5 (MA-5) is a synthesized indole derivative targeting the mitochondrial protein mitofilin, modulates mitochondrial ATP synthesis independently of oxidative phosphorylation and the electron transport chain. |
| PC-24788 |
SANA
Thermogenesis inducer
|
SANA is a nitroalkene derivative of salicylate, and a first-in-class activator of creatine-dependent energy expenditure and thermogenesis, induces creatine-dependent thermogenesis and promotes weight loss. |
| PC-24771 |
Kaempferol
MARK4 inhibitor
|
Kaempferol is a natural MARK4 inhibitor with IC50 of 11.54 uM, also inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. |
| PC-24758 |
CD39 inhibitor Compound 338
CD39 inhibitor
|
CD39 inhibitor compound 338 is a potent, selective nucleotidase NTPDase1 (CD39) inhibitor with IC50 of 68.7 nM, weakly inhibits NTPDase 2 and NTPDase 3, with IC50 values of 975.9 nM and 715.9 nM, respectively. |
