AEBSF hydrochloride | Serine protease inhibitor | Probechem Biochemicals

Chemical Structure : AEBSF

CAS No.: 30827-99-7

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AEBSF (AEBSF hydrochloride, Serine protease inhibitor)

货号: PC-43231Not For Human Use, Lab Use Only.

AEBSF is an irreversible serine protease inhibitor that inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.

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100 mg	￥480	In stock
250 mg	￥780	In stock
1 g		Get quote

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生物&药学活性

AEBSF is an irreversible serine protease inhibitor that inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.
AEBSF inhibits the constitutive production of Aβ by directly inhibiting β-secretase in different human cell lines, both neural and nonneural.
AEBSF inhibits the lysis of leukemic cells by human macrophages without inhibiting macrophage secretion of TNF-α and IL-1β.
AEBSF also disturbs the growth of blastocysts on endometrial cells and inhibits the adhesion of HeLa cells on HUVECs by altering the protein secretion pattern.
AEBSF inhibits the rat embryo implantation in vivo.

物理化学性质&存储条件

分子量	239.6948
分子式	C8H11ClFNO2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 30 mg/mL
Chemical Name/SMILES	Benzenesulfonyl fluoride, 4-(2-aminoethyl)-, hydrochloride (1:1)

参考文献

1. Citron M, et al. Neuron. 1996 Jul;17(1):171-9.

2. Nakabo Y, et al. J Leukoc Biol. 1996 Sep;60(3):328-36.

3. Buitrago-Rey R, et al. J Antimicrob Chemother. 2002 May;49(5):871-4.

4. Jiang YH, et al. Contraception. 2011 Dec;84(6):642-8.

AEBSF (AEBSF hydrochloride, Serine protease inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

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AEBSF (AEBSF hydrochloride, Serine protease inhibitor)

生物&药学活性

物理化学性质&存储条件

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