KHK-IN-8 hydrochloride |CAS:1303470-48-5 Probechem Biochemicals

Chemical Structure : KHK-IN-8 hydrochloride

CAS No.: 1303470-48-5

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KHK-IN-8 hydrochloride (Ketohexokinase inhibitor 8)

货号: PC-43253Not For Human Use, Lab Use Only.

KHK-IN-8 hydrochloride is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp-27B in the ATP-binding region of KHK, also shows potent cellular KHK inhibition with IC50 of <500 nM.

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1 mg	￥1380	In stock
5 mg	￥2980	In stock
10 mg	￥4980	In stock
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100 mg		Get quote

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生物&药学活性

KHK-IN-8 hydrochloride is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp-27B in the ATP-binding region of KHK, also shows potent cellular KHK inhibition with IC50 of <500 nM.

物理化学性质&存储条件

分子量	459.0107
分子式	C21H27ClN8S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Pyrimido[5,4-d]pyrimidine-4,8-diamine, N8-(cyclopropylmethyl)-N4-[2-(methylthio)phenyl]-2-(1-piperazinyl)-, hydrochloride (1:1)

参考文献

1. Maryanoff BE, et al. ACS Med Chem Lett. 2011 Apr 18;2(7):538-43.

2. Maryanoff BE, et al. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5326-9.

KHK-IN-8 hydrochloride (Ketohexokinase inhibitor 8)

生物&药学活性

物理化学性质&存储条件

参考文献

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KHK-IN-8 hydrochloride (Ketohexokinase inhibitor 8)

生物&药学活性

物理化学性质&存储条件

参考文献

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