| Cat. No. |
Product Name |
Information |
| PC-24905 |
IR-546
NIR fluorescent
|
IR-546 is a NIR fluorescent probe, inhibits melanoma cell proliferation by activating the mitochondrial apoptosis pathway through suppression of the AKT/GSK3β signaling pathway. |
| PC-24845 |
Sardomozide dihydrochloride
SAMDC inhibitor
|
SAM486A dihydrochloride (Sardomozide) is a highly potent, selective S-adenosylmethionine decarboxylase (SAMDC) inhibitor with IC50 of 5 nM, inhibits intracellular spermidine and spermine pools. |
| PC-24844 |
SAM486A
SAMDC inhibitor
|
SAM486A (Sardomozide) is a highly potent, selective S-adenosylmethionine decarboxylase (SAMDC) inhibitor with IC50 of 5 nM, inhibits intracellular spermidine and spermine pools. |
| PC-24839 |
NGI-186
Oligosaccharyltransferase inhibitor
|
NGI-186 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.06 uM. |
| PC-24838 |
NGI-190
Oligosaccharyltransferase inhibitor
|
NGI-190 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.59 uM. |
| PC-24833 |
Pinosylvin
CAS 22139-77-1
|
Pinosylvin is a naturally occurring molecule traditionally found in pinus trees with antibacterial, antifungal and anticancer activity, shows potent growth inhibitory activity against Candida albicans and Saccharomyces cerevisiae. |
| PC-24820 |
KS122-0485428
Lysyl hydroxylase 2 inhibitor
|
KS122-0485428 is a specific small molecule inhibitor of Lysyl hydroxylase 2 (LH2), significantly enhances LH2 function in telopeptidyl Lys hydroxylation, cross-linking, and mineralization. |
| PC-24811 |
NSD-1015
AADC inhibitor
|
NSD-1015 (3-Hydroxybenzylhydrazine) is a specific small molecule inhibitor of aromatic L-amino acid decarboxylase (AADC). |
| PC-24805 |
Benserazide hydrochloride
AADC inhibitor,
|
Benserazide hydrochloride is a selective, peripherally acting aromatic L-amino acid decarboxylase (AADC) inhibitor, also is a potent inhibitor of bacterial T4P assembly ATPase PilB with IC50 of 3.68 uM. |
| PC-24791 |
TREM2 activator 4a
TREM2 agonist
|
TREM2 activator 4a is a specific small molecule activator of triggering receptor expressed on myeloid cells 2 (TREM2) with KD of 12.7 uM, 1.5-fold selectivity over TREM1, induces SYK phosphorylation and significantly enhances microglial phagocytic activity. |
| PC-24790 |
TREM2 activator 4i
TREM2 agonist
|
TREM2 activator 4i is a specific small molecule activator of triggering receptor expressed on myeloid cells 2 (TREM2) with KD of 19.0 uM in MST assays, 2-fold selectivity over TREM1, induces SYK phosphorylation and significantly enhances microglial phagocytic activity. |
| PC-24789 |
Mitochonic acid 5
ATP synthesis modulator
|
Mitochonic acid 5 (MA-5) is a synthesized indole derivative targeting the mitochondrial protein mitofilin, modulates mitochondrial ATP synthesis independently of oxidative phosphorylation and the electron transport chain. |
