| Cat. No. |
Product Name |
Information |
| PC-26922 |
GPR52 agonist R-185
GPR52 agonist
|
GPR52 agonist R-185 is a potent, selective, brain permeable and orally available GPR52 agonist with EC50 of 26 nM, significantly inhibits MK-801-induced hyperlocomotor behaviors in zebrafish larvae and mice. |
| PC-26921 |
GPR52 agonist 1
GPR52 agonist
|
GPR52 agonist 1 is a potent, BBB- penetrant and orally available agonist of orphan G-protein-coupled receptor 52 (GPR52) with pEC50 of 7.53, suppresses methamphetamine-induced hyperactivity in vivo. |
| PC-26920 |
B0045
VprBP inhibitor
|
B0045 is a specific, second-generation inhibitor of DCAF1 (Vpr-binding protein, VprBP), blocks VprBP-mediated H2AT120p and reactivates growth regulatory genes, resulting in a significantly lower proliferative capacity of prostate cancer cells. |
| PC-26919 |
SSKP-0076
Ybx1 inhibitor
|
SSKP-0076 is a small molecule inhibitor of Y-box binding protein 1 (Ybx1), inhibits invasion and migration of LM8 osteosarcoma cells. |
| PC-26911 |
IRG1-IN-1
IRG1 inhibitor
|
IRG1-IN-1 is an itaconic acid derivative and inhibitor of immune-responsive gene 1 (IRG1) activity. |
| PC-26910 |
CVM-05-002
PI5P4K inhibitor
|
CVM-05-002 is a potent and selective inhibitor of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) with IC50 of 0.27 uM and 1.69 uM for PI5P4Kα and PI5P4Kβ。 |
| PC-26909 |
066ATZ
PIP4K2A/2B inhibitor
|
066ATZ is a potent, selective dual PIP4K2A and PIP4K2B inhibitor with Ki of 100 nM and 800 nM. |
| PC-26907 |
Fexlamose
Mucolytic
|
Fexlamose (AER-01, MUC-031) is a potent and fast-acting mucolytic compound, cleaves disulfides to cause mucolysis, shows potential for muco-obstructive lung diseases like COPD (Chronic Obstructive Pulmonary Disease) and asthma. |
| PC-26904 |
ADGRL1 inhibitor compound 2
ADGRL1 inhibitor
|
ADGRL1 inhibitor compound 2 is a potential small molecule inhibitor of adhesion G protein-coupled receptor L1 (ADGRL1/Latrophilin-1), activates the GSK3β-STAT1 axis in CT26 cells in vitro, consistent with the knockdown of Adgrl1. |
| PC-26902 |
CPN-351 TFA
NMUR1 antagonist
|
CPN-351 TFA is a potent, selective pentapeptide antagonist of Neuromedin U Receptor 1 (NMUR1) with pA2 and KB values of 7.35 and 45 nM, respectively, selective over NMUR2 with 6.38 and 421 nM, respectively. |
| PC-26901 |
CPN-351
NMUR1 antagonist
|
CPN-351 is a potent, selective pentapeptide antagonist of Neuromedin U Receptor 1 (NMUR1) with pA2 and KB values of 7.35 and 45 nM, respectively, selective over NMUR2 with 6.38 and 421 nM, respectively. |
| PC-26890 |
Sinbaglustat
GCS/GBA2 inhibitor
|
Sinbaglustat (OGT2378) is an orally available, blood-brain barrier permeable dual inhibitor of glucosylceramide synthase (GCS) and non-lysosomal glucosyl ceramidase (GBA2), Sinbaglustat is 50‐fold more potent in inhibiting GBA2 than GCS. |
