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首页-小分子抑制剂&激动剂-Others-Other Targets-CH-5450
CH-5450

Chemical Structure : CH-5450

CAS No.: 252557-97-4

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CH-5450 (Z-Ile-Glu-Pro-Phe-CO2Me, CH5450)

货号: PC-45053Not For Human Use, Lab Use Only.

CH-5450 is a potent, peptide-inhibitor of human chymase with Ki of 1 nM.

规格 价格 库存 数量
5 mg ￥1580 In stock
10 mg ￥2480 In stock
25 mg ￥4280 In stock
50 mg Get quote
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CH-5450 is a potent, peptide-inhibitor of human chymase with Ki of 1 nM.
CH-5450 causes an almost complete inhibition of the AI-induced contractions combined with Enalaprilat.
CH-5450 depresses the (Pro11-,D-Ala12)-AI-induced contractions at 10 uM.

物理化学性质&存储条件

分子量 652.7346
分子式 C34H44N4O9
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 43 mg/mL
Chemical Name/SMILES

L-Phenylalanine, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-L-prolyl-, 4-methyl ester

参考文献

1. Bastos M, et al. Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):6738-42.

2. Waldeck K, et al. Br J Pharmacol. 1997 Jul;121(6):1081-6.

3. He S, et al. J Pharmacol Exp Ther. 1999 Nov;291(2):517-23.

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